Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 2/20 | 0.32 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL417994 | 0.90 | LTA4H (0.38) | LTA4HPCSK9TSHRTDP1PTGS2 | |
| SCHEMBL2266534 | 0.88 | TP53 (0.31) | SMN1; SMN2 | |
| SCHEMBL12816111 | 0.86 | LTA4H (0.33) | PTPN1LTA4HPCSK9TSHRTDP1 | |
| SCHEMBL31216297 | 0.85 | TSHR (0.46) | PTPN1LTA4HTSHRTDP1NPC1 | |
| SCHEMBL418321 | 0.84 | LTA4H (0.38) | LTA4HPCSK9SMN1; SMN2SIGMAR1CES2 | |
| SCHEMBL9643720 | 0.82 | DNM1 (0.40) | SMN1; SMN2SIGMAR1CES2CES1 | |
| SCHEMBL418038 | 0.82 | DNM1 (0.40) | SMN1; SMN2SIGMAR1CES2CES1 | |
| SCHEMBL8992386 | 0.82 | DNM1 (0.40) | SMN1; SMN2SIGMAR1CES2CES1 | |
| SCHEMBL415280 | 0.82 | DNM1 (0.40) | SMN1; SMN2SIGMAR1CES2CES1 | |
| SCHEMBL8992249 | 0.82 | CES2 (0.37) | LTA4HPCSK9PTGS2NPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5100762-A | Radiation-sensitive polymer and radiation-sensitive composition containing the same | MITSUBISHI DENKI KABUSHIKI KAISHA (JP) | 1992-03-31 | — | — | US | disclosed |