SCHEMBL8992595

SCHEMBL8992595

Cc1ccccc1NC(=O)c1cc2ccccc2c(/N=N/c2cc(Cl)c(Cl)cc2Cl)c1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.49
CYP1A2 P05177 1/20 0.49
NQO2 P16083 1/20 0.46
LMNA P02545 4/20 0.43
POLB P06746 4/20 0.43
NPC1 O15118 4/20 0.43
KDM4E B2RXH2 2/20 0.43
HTT P42858 2/20 0.43
RAB9A P51151 2/20 0.43
MAOB P27338 1/20 0.43
MAPT P10636 1/20 0.43
NPY1R P25929 1/20 0.43
NPY2R P49146 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
AKR1C3 P42330 1/20 0.43
HPGD P15428 2/20 0.43
MAPK1 P28482 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TNF P01375 1/20 0.42
NOD1 Q9Y239 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29356409 1.00 ALDH1A1 (0.49) ALDH1A1CYP1A2NQO2LMNAPOLB
SCHEMBL29687187 1.00 ALDH1A1 (0.49) ALDH1A1CYP1A2NQO2LMNAPOLB
SCHEMBL13128929 1.00 ALDH1A1 (0.49) ALDH1A1CYP1A2NQO2LMNAPOLB
Calcium SCHEMBL30553119 0.99 ALDH1A1 (0.48) ALDH1A1CYP1A2NQO2LMNAPOLB
SCHEMBL31333185 0.94 ALDH1A1 (0.43) ALDH1A1CYP1A2NQO2LMNAPOLB
SCHEMBL29687533 0.90 LMNA (0.49) ALDH1A1CYP1A2NQO2LMNAPOLB
SCHEMBL12967085 0.90 ALDH1A1 (0.50) ALDH1A1CYP1A2NQO2LMNAPOLB
SCHEMBL21436604 0.89 ALDH1A1 (0.52) ALDH1A1CYP1A2NQO2LMNAPOLB
SCHEMBL17804092 0.84 LMNA (0.48) ALDH1A1CYP1A2NQO2LMNAPOLB
SCHEMBL17804076 0.84 THRB (0.54) ALDH1A1CYP1A2NQO2LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10907056-B2 Curable compositions BLUE CUBE IP LLC (US) 2021-02-02 US disclosed
EP-3271428-B1 CURABLE COMPOSITIONS BLUE CUBE IP LLC (US) 2020-11-11 EP disclosed
EP-3271429-B1 CURABLE COMPOSITIONS BLUE CUBE IP LLC (US) 2020-05-06 EP disclosed
US-10442941-B2 Curable compositions BLUE CUBE IP LLC (US) 2019-10-15 US disclosed
US-20180100076-A1 CURABLE COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC 2018-04-12 US disclosed
US-20180100076-A1 CURABLE COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC 2018-04-12 US disclosed
US-20180072900-A1 CURABLE COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC 2018-03-15 US disclosed
US-20180072900-A1 CURABLE COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC 2018-03-15 US disclosed
US-9504637-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2016-11-29 US disclosed
WO-2016160346-A1 CURABLE COMPOSITIONS BLUE CUBE IP LLC (US) 2016-10-06 WO disclosed
US-20110154583-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. (US) 2011-06-30 US disclosed
EP-2139347-B1 USE OF WATER-DISPERSIBLE CAROTINOID NANOPARTICLES AS TASTE MODULATORS, TASTE MODULATORS CONTAINING WATER-DISPERSIBLE CAROTINOID NANOPARTICLES, AND METHOD FOR TASTE MODULATION BRAIN BIOTECHNOLOGY RES & INFORMATION NETWORK AG (DE) 2011-01-12 EP disclosed
US-20100047426-A1 METHOD FOR MODULATING THE TASTE OF MATERIAL COMPOSITIONS CONTAINING AT LEAST ONE HIGH INTENSITY SWEETENER (HIS) BASF SE (DE) 2010-02-25 US disclosed
US-20100047426-A1 METHOD FOR MODULATING THE TASTE OF MATERIAL COMPOSITIONS CONTAINING AT LEAST ONE HIGH INTENSITY SWEETENER (HIS) BASF SE (DE) 2010-02-25 US disclosed
US-20100028444-A1 USE OF WATER-DISPERSIBLE CAROTENOID NANOPARTICLES AS TASTE MODULATORS, TASTE MODULATORS CONTAINING WATER-DISPERSIBLE CAROTENOID NANOPARTICLES, AND, METHOD FOR TASTE MODULATION BASF SE (DE) 2010-02-04 US disclosed
US-20100028444-A1 USE OF WATER-DISPERSIBLE CAROTENOID NANOPARTICLES AS TASTE MODULATORS, TASTE MODULATORS CONTAINING WATER-DISPERSIBLE CAROTENOID NANOPARTICLES, AND, METHOD FOR TASTE MODULATION BASF SE (DE) 2010-02-04 US disclosed
WO-2008102018-A2 METHOD FOR MODULATING THE TASTE OF MATERIAL COMPISITIONS CONTAINING AT LEAST ONE HIGH INTENSITY SWEETENER (HIS) BASF SE (DE) 2008-08-28 WO disclosed
WO-2008102019-A2 USE OF WATER-DISPERSIBLE CAROTINOID NANOPARTICLES AS TASTE MODULATORS, TASTE MODULATORS CONTAINING WATER-DISPERSIBLE CAROTINOID NANOPARTICLES, AND METHOD FOR TASTE MODULATION BASF SE (DE) 2008-08-28 WO disclosed
US-20070141504-A1 Liquid developer SEIKO EPSON CORPORATION 2007-06-21 US disclosed
US-20070141504-A1 Liquid developer SEIKO EPSON CORPORATION 2007-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110154583-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 ALDH1A1 192/4885CYP1A2 1159/4885NQO2 638/4885
US-20100028444-A1 USE OF WATER-DISPERSIBLE CAROTENOID NANOPARTICLES AS TASTE MODULATORS, TASTE MODULATORS CONTAINING WATER-DISPERSIBLE CAROTENOID NANOPARTICLES, AND, METHOD FOR TASTE MODULATION TAS2R13, TAS2R10, TAS2R16 ALDH1A1 2079/4885CYP1A2 2613/4885NQO2 2443/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.