Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625612 | 0.87 | ENPP2 (0.53) | KDM4ETAAR1ENPP2IDO1TDP1 | |
| SCHEMBL8093804 | 0.84 | TAAR1 (0.56) | LTA4HTAAR1IDO1SAE1UBA2 | |
| SCHEMBL8992798 | 0.82 | ENPP2 (0.41) | LTA4HKDM4ETAAR1ENPP2IDO1 | |
| SCHEMBL20257530 | 0.82 | LOXL2 (0.48) | LTA4HKDM4ETAAR1IDO1SAE1 | |
| SCHEMBL8085716 | 0.81 | CALM1 (0.55) | LTA4HTAAR1IDO1SAE1UBA2 | |
| SCHEMBL8993250 | 0.81 | SRD5A2 (0.41) | LTA4HKDM4ETAAR1IDO1TDP1 | |
| SCHEMBL11087087 | 0.81 | LTA4H (0.53) | LTA4HTAAR1IDO1TDP1SAE1 | |
| SCHEMBL29459538 | 0.80 | TAAR1 (0.60) | LTA4HTAAR1IDO1DAOACHE | |
| SCHEMBL1263547 | 0.80 | TAAR1 (0.60) | LTA4HTAAR1IDO1DAOACHE | |
| SCHEMBL30000562 | 0.80 | TAAR1 (0.60) | LTA4HTAAR1IDO1DAOACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |