SCHEMBL899344

SCHEMBL899344

Fc1c(Br)cccc1C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ULK1 O75385 1/20 0.40
MPL P40238 3/20 0.40
HSD11B1 P28845 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA9 Q16790 2/20 0.39
CA5A P35218 1/20 0.39
IDO1 P14902 1/20 0.39
TDO2 P48775 1/20 0.39
P2RX7 Q99572 2/20 0.37
CA12 O43570 1/20 0.36
LMNA P02545 1/20 0.35
GAA P10253 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.34
ALDH1A1 P00352 1/20 0.34
POLB P06746 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
AXL P30530 1/20 0.34
KIF11 P52732 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31618847 1.00 ULK1 (0.40) ULK1MPLHSD11B1SMN1; SMN2CA1
SCHEMBL28507045 0.86 CA1 (0.39) ULK1HSD11B1SMN1; SMN2CA1CA2
SCHEMBL17295713 0.82 CA1 (0.37) ULK1HSD11B1SMN1; SMN2CA1CA2
SCHEMBL2030240 0.82 CA2 (0.37) ULK1HSD11B1SMN1; SMN2CA1CA2
SCHEMBL29656443 0.82 CA2 (0.37) ULK1HSD11B1SMN1; SMN2CA1CA2
SCHEMBL7601747 0.82 MPL (0.46) MPLHSD11B1CA2IDO1TDO2
SCHEMBL26762115 0.79 CA2 (0.44) ULK1HSD11B1CA1CA2CA9
SCHEMBL7191759 0.78 TAS2R14 (0.42) HSD11B1SMN1; SMN2CA1CA2CA9
SCHEMBL1568066 0.78 PDE2A (0.38) ULK1MPLHSD11B1SMN1; SMN2LMNA
SCHEMBL30730980 0.78 PDE2A (0.38) ULK1MPLHSD11B1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230301186-A1 ORGANIC TRIAZINE CONTAINING MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-21 US claimed
EP-4185581-A1 ORGANIC TRIAZINE CONTAINING MOLECULES FOR USE IN OPTOELECTRONIC DEVICES Samsung Display Co., Ltd. (KR) 2023-05-31 EP claimed
CN-116157408-A Triazine-containing organic molecules for optoelectronic devices 三星显示有限公司 2023-05-23 CN claimed
WO-2022018175-A1 ORGANIC TRIAZINE CONTAINING MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2022-01-27 WO claimed
EP-3543319-A1 METHOD OF MARKING HYDROCARBON LIQUIDS Johnson Matthey Public Limited Company (GB) 2019-09-25 EP claimed
US-20140120626-A1 METHOD OF MARKING HYDROCARBON LIQUIDS JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2014-05-01 US claimed
EP-2707465-A1 METHOD OF MARKING HYDROCARBON LIQUIDS Johnson Matthey Public Limited Company (GB) 2014-03-19 EP claimed
WO-2012153132-A1 METHOD OF MARKING HYDROCARBON LIQUIDS JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2012-11-15 WO claimed
EP-4743078-A2 APOL1 INHIBITORS AND METHODS OF USE Maze Therapeutics, Inc. (US) 2026-05-20 EP disclosed
EP-4743079-A2 APOL1 INHIBITORS AND METHODS OF USE THEREOF Maze Therapeutics, Inc. (US) 2026-05-20 EP disclosed
EP-4667458-A1 PHARMACEUTICAL COMPOSITION FOR TREATMENT OF CANCER, COMPRISING SOS1 INHIBITOR AND ANTICANCER DRUG Kanaph Therapeutics Inc. (KR) 2025-12-24 EP disclosed
EP-4667464-A1 AZOLYLPYRIDINE PYRIDAZINONE AMIDE AS SOS1 INHIBITOR Cyrus Therapeutics Inc. (KR) 2025-12-24 EP disclosed
US-20250320196-A1 APOL1 INHIBITORS AND METHODS OF USES THEREOF MAZE THERAPEUTICS INC (US) 2025-10-16 US disclosed
US-12421191-B2 3-hydroxyoxindole derivatives as CRHR2 antagonist RAQUALIA PHARMA INC. (JP) 2025-09-23 US disclosed
WO-1996035422-A1 METHODS FOR INHIBITING BONE LOSS ELI LILLY AND COMPANY (US) 1996-11-14 WO disclosed
EP-0742010-A2 Benzoquinolin-3-ones to inhibit bone loss ELI LILLY AND COMPANY (US) 1996-11-13 EP disclosed
EP-0733365-A2 Use of benzoquinolin-3-ones for the treatment and prevention of prostatic cancer ELI LILLY AND COMPANY (US) 1996-09-25 EP disclosed
US-5550134-A ADMINISTERING TO A MAMMAL FROM A SERIES OF BENZOQUINOLIN-3-ONE COMPOUNDS ELI LILLY AND COMPANY (US) 1996-08-27 US disclosed
EP-0113625-B1 PROCESS FOR THE PREPARATION OF TRIFLUOROMETHYLATED BENZENIC COMPOUNDS RHONE-POULENC CHIMIE (FR) 1985-07-10 EP disclosed
EP-0113625-A1 Process for the preparation of trifluoromethylated benzenic compounds RHONE-POULENC CHIMIE (FR) 1984-07-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12421191-B2 3-hydroxyoxindole derivatives as CRHR2 antagonist CRHR2, CRHR1, CRH ULK1 1346/4885MPL 3805/4885HSD11B1 68/4885
US-20250320196-A1 APOL1 INHIBITORS AND METHODS OF USES THEREOF APOL1, APOB, LDLR ULK1 1219/4885MPL 4471/4885HSD11B1 379/4885
US-20230301186-A1 ORGANIC TRIAZINE CONTAINING MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OXER1, OXSR1, OR10J3 ULK1 4593/4885MPL 1564/4885HSD11B1 2041/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.