Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993563 | 0.87 | PTGS2 (0.35) | — | |
| SCHEMBL8993537 | 0.82 | — | — | |
| SCHEMBL8993451 | 0.62 | PTGS2 (0.39) | — | |
| SCHEMBL8993449 | 0.60 | PTGS2 (0.45) | CSF1RGRM2 | |
| SCHEMBL8993654 | 0.59 | F2RL1 (0.36) | GRM2 | |
| SCHEMBL8993514 | 0.59 | PTGS2 (0.52) | GRM2 | |
| SCHEMBL8993495 | 0.57 | PIM1 (0.37) | GRM2 | |
| SCHEMBL8993549 | 0.57 | PTGES2 (0.36) | GRM2 | |
| SCHEMBL6733073 | 0.56 | PTGES2 (0.49) | GRM2 | |
| SCHEMBL20401017 | 0.56 | ACMSD (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724566-A1 | 1,2-DIARYLCYCLOPENTENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995011883-A1 | 1,2-DIARYLCYCLOPENTENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1995-05-04 | — | — | WO | disclosed |