SCHEMBL8994481

SCHEMBL8994481

N#Cc1c(Cl)c(Cl)n(COC(=O)C2CC2)c1-c1ccc(C(F)(F)F)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.36
DHODH Q02127 1/20 0.36
L3MBTL1 Q9Y468 3/20 0.35
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
ALOX5 P09917 1/20 0.34
AOC3 Q16853 1/20 0.33
ADORA1 P30542 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
KDM2B Q8NHM5 2/20 0.33
APP P05067 1/20 0.33
PSEN1 P49768 1/20 0.33
PSEN2 P49810 1/20 0.33
APH1B Q8WW43 1/20 0.33
NCSTN Q92542 1/20 0.33
APH1A Q96BI3 1/20 0.33
PSENEN Q9NZ42 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8994414 0.95 MGLL (0.36) MGLLL3MBTL1KDM4EALDH1A1POLB
SCHEMBL9222722 0.85 ADORA1 (0.35) DHODHADORA1ALDH1A1MAPTPSEN1
SCHEMBL8994386 0.80 PAX8 (0.35) L3MBTL1KMT2AMEN1ALDH1A1POLB
SCHEMBL8994464 0.78 L3MBTL1 (0.34) MGLLL3MBTL1KMT2AMEN1KDM4E
SCHEMBL8072565 0.77 KIF11 (0.36) DHODHADORA1ALDH1A1MAPT
SCHEMBL9059293 0.75 KIF11 (0.41) DHODHKMT2AMEN1ADORA1KDM4E
SCHEMBL8994389 0.75 ADORA1 (0.34) ADORA1POLBMAPTAPP
SCHEMBL9461475 0.75 L3MBTL1 (0.39) L3MBTL1KMT2AMEN1KDM4EALDH1A1
SCHEMBL9057391 0.74 GRIA2 (0.38) ADORA1ALDH1A1APP
SCHEMBL8994395 0.74 ALDH1A1 (0.33) L3MBTL1KMT2AMEN1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0594941-B1 N-substituted carbonyoxyalkylpyrrole insecticidal, acaricidal and molluscicidal agents AMERICAN CYANAMID CO (US) 1996-08-14 EP claimed
EP-0594941-A1 N-substituted carbonyoxyalkylpyrrole insecticidal, acaricidal and molluscicidal agents AMERICAN CYANAMID COMPANY (US) 1994-05-04 EP claimed
US-5232980-A Insecticides, miticides, molluscicides AMERICAN CYANAMID COMPANY (US) 1993-08-03 US claimed