Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 11/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 8/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | HPN | P05981 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7418020 | 0.84 | ITGB3 (0.62) | PSMB8NPY5RPSMB5ITGB3ITGA2B | |
| SCHEMBL7418027 | 0.84 | ITGB3 (0.62) | PSMB8NPY5RPSMB5ITGB3ITGA2B | |
| SCHEMBL8995559 | 0.79 | KMT2A (0.44) | ALDH1A1HPGD | |
| SCHEMBL7423101 | 0.77 | S1PR2 (0.38) | ITGB3ITGA2B | |
| SCHEMBL7320119 | 0.75 | RAB9A (0.43) | ITGB3ITGA2BALDH1A1 | |
| SCHEMBL7414356 | 0.74 | CASP1 (0.52) | ITGB3ITGA2B | |
| SCHEMBL7417109 | 0.74 | CASP1 (0.52) | ITGB3ITGA2B | |
| SCHEMBL7384441 | 0.73 | EPHX2 (0.49) | ITGB3ITGA2BALDH1A1HPGD | |
| SCHEMBL8995540 | 0.73 | KMT2A (0.38) | ITGB3ITGA2BALDH1A1HPGD | |
| SCHEMBL4857259 | 0.72 | NPY5R (0.62) | PSMB8NPY5RPSMB5MMP2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552431-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1996-09-03 | — | — | US | disclosed |
| US-5424334-A | Peptide mimetic compounds useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-06-13 | — | — | US | disclosed |
| WO-1993012074-A1 | PEPTIDE MIMETIC COMPOUNDS USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1993-06-24 | — | — | WO | disclosed |