Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 4/20 | 0.34 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997612 | 0.89 | SYK (0.41) | SYKCTSKCTSBCA1CA2 | |
| SCHEMBL8997623 | 0.88 | GHSR (0.34) | GHSR | |
| SCHEMBL8997761 | 0.85 | GHSR (0.33) | GHSR | |
| SCHEMBL8997594 | 0.80 | SYK (0.40) | SYKCTSKCA1CA2ACHE | |
| SCHEMBL8582293 | 0.78 | SYK (0.44) | SYKCTSKCTSLCTSSCTSB | |
| SCHEMBL8997804 | 0.78 | P2RY1 (0.37) | SYKCTSKCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8997619 | 0.78 | GHSR (0.35) | CYP1A2LMNAGHSRCYP2C9TSHR | |
| SCHEMBL8997596 | 0.77 | GHSR (0.35) | LMNAGHSRTSHR | |
| SCHEMBL8997607 | 0.77 | GHSR (0.35) | CYP1A2LMNAGHSRCYP2C9TSHR | |
| SCHEMBL8997600 | 0.76 | SYK (0.40) | SYKCA1CA2ACHECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729972-A1 | Peptide derivatives of tetrahydronaphthalene | F. HOFFMANN-LA ROCHE AG (CH) | 1996-09-04 | — | — | EP | disclosed |