Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.44 |
| ▸ | ATIC | P31939 | 3/20 | 0.40 |
| ▸ | SHMT1 | P34896 | 3/20 | 0.40 |
| ▸ | SHMT2 | P34897 | 3/20 | 0.40 |
| ▸ | GART | P22102 | 2/20 | 0.38 |
| ▸ | EP300 | Q09472 | 4/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563771 | 0.91 | TLR7 (0.45) | TLR7ATICSHMT1SHMT2GART | |
| SCHEMBL8570678 | 0.82 | ATIC (0.38) | TLR7ATICSHMT1SHMT2GART | |
| SCHEMBL9446061 | 0.77 | TLR8 (0.39) | TLR7TLR8 | |
| SCHEMBL8563902 | 0.76 | TLR7 (0.50) | TLR7ATICSHMT1SHMT2GART | |
| SCHEMBL7653891 | 0.73 | CA12 (0.43) | TLR7TLR8SIRT2SIRT1CA12 | |
| SCHEMBL9001870 | 0.73 | ATIC (0.73) | ATICSHMT1SHMT2GART | |
| SCHEMBL8567733 | 0.73 | CRHBP (0.41) | EP300SIRT2SIRT1CA12CA1 | |
| SCHEMBL8562850 | 0.73 | CYP4A11 (0.35) | EP300SIRT2SIRT1CA12CA1 | |
| SCHEMBL8564673 | 0.73 | ATIC (0.43) | TLR7ATICSHMT1SHMT2GART | |
| SCHEMBL8564668 | 0.72 | ATIC (0.48) | TLR7ATICSHMT1SHMT2GART |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554615-A | ANTITUMOR | EISAI CO., LTD. (JP) | 1996-09-10 | — | — | US | disclosed |
| EP-0530579-A1 | Condensed pyrimidine derivatives antitumor agents | Eisai Co., Ltd. (JP) | 1993-03-10 | — | — | EP | disclosed |