Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.32 |
| ▸ | CASP6 | P55212 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 8/20 | 0.31 |
| ▸ | NPC1 | O15118 | 6/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8635712 | 0.88 | MAPT (0.32) | ALDH1A1SMN1; SMN2CASP6MAPTRAB9A | |
| SCHEMBL8636623 | 0.87 | CASP6 (0.41) | ALDH1A1SMN1; SMN2CASP6MAPTRAB9A | |
| SCHEMBL8640361 | 0.84 | PLCG1 (0.40) | ALDH1A1SMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL8637410 | 0.80 | ITGB3 (0.32) | ALDH1A1SMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL8638609 | 0.79 | CYP1A2 (0.40) | ALDH1A1SMN1; SMN2MAPTCYP1A2CYP2C19 | |
| SCHEMBL6436979 | 0.79 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL8637170 | 0.79 | MAPT (0.35) | ALDH1A1MAPTRAB9AKMT2A | |
| SCHEMBL9173014 | 0.79 | MAOB (0.35) | MAPTMEN1MAPK1KMT2A | |
| SCHEMBL8635639 | 0.77 | CASP1 (0.39) | ALDH1A1CASP6RAB9ANPC1MEN1 | |
| SCHEMBL9004590 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480882-A | Benzoxazinone and benzothiazinone derivatives having cardiovascular activity | ITALFARMACO S.P.A. (IT) | 1996-01-02 | — | — | US | claimed |