SCHEMBL90077

SCHEMBL90077

CCC1CN(C)CCN1C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KAT6A Q92794 1/20 0.32
NCF1 P14598 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14948558 1.00 KAT6A (0.32) KAT6ANCF1
SCHEMBL14948548 1.00 KAT6A (0.32) KAT6ANCF1
SCHEMBL2048600 0.98 NCF1 (0.34) KAT6ANCF1
SCHEMBL20161410 0.86 CYP1A2 (0.35)
SCHEMBL16707752 0.86 CYP1A2 (0.35)
SCHEMBL20161474 0.86 CYP1A2 (0.35)
SCHEMBL26814535 0.81 SLC6A3 (0.33)
SCHEMBL9801833 0.81 SLC6A3 (0.33)
SCHEMBL14664303 0.81 SLC6A3 (0.33)
SCHEMBL7374703 0.80 SIGMAR1 (0.32) NCF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109384246-A A kind of AEI structure molecular screen and its preparation method and application 中触媒新材料股份有限公司 2019-02-26 CN claimed
WO-2023184327-A1 KINASE INHIBITORS, PREPARATION METHODS AND USES THEREOF InventisBio Co., Ltd. (CN) 2023-10-05 WO disclosed
EP-4223285-A2 METHOD OF ENCAPSULATING A NUCLEIC ACID IN A LIPID NANOPARTICLE HOST Novartis AG (CH) 2023-08-09 EP disclosed
US-20230219986-A1 NOVEL AMINOPYRIMIDINE EGFR INHIBITOR QILU PHARMACEUTICAL CO., LTD. (CN) 2023-07-13 US disclosed
WO-2023107648-A2 SYNTHESIS OF ESTER, CARBONATE, AND CARBAMATE-DERIVED NOVEL BIODEGRADABLE IONIZABLE LIPIDS FROM METHYL RICINOLEATE OR METHYL 12-HYDROXYSTEARATE AND ITS APPLICATIONS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-06-15 WO disclosed
US-20230146127-A1 3-DIARYLMETHYLENES AND USES THEREOF ATUX ISKAY LLC 2023-05-11 US disclosed
EP-3169309-B1 METHOD OF ENCAPSULATING A NUCLEIC ACID IN A LIPID NANOPARTICLE HOST NOVARTIS AG (CH) 2023-05-10 EP disclosed
EP-3507275-B1 CXCR3 RECEPTOR AGONISTS RECEPTOS LLC (US) 2023-04-26 EP disclosed
WO-2023006893-A1 COMPOUNDS FOR THE TREATMENT OF PAIN, IN PARTICULAR NEUROPATHIC PAIN, AND/OR OTHER DISEASES OR DISORDERS THAT ARE ASSOCIATED WITH AT2R AND/OR AT2R MEDIATED SIGNALING CONFO THERAPEUTICS N.V. (BE) 2023-02-02 WO disclosed
WO-2023006013-A1 NOVEL PARP7 INHIBITOR AND USE THEREOF 上海齐鲁制药研究中心有限公司 2023-02-02 WO disclosed
US-20080138427-A1 Reduced variation in the dissolution profile of a biologically active substance; pharmaceutical, drug sprayed while spraying a binding liquid to the cores; centrifugal fluidized bed coating granulation machine set to1.5 g/cm2 TAKEDA PHARMACEUTICAL COMPANY (JP) 2008-06-12 US disclosed
US-7384934-B2 Piperazine substituted aryl benzodiazepines ELI LILLY AND COMPANY (US) 2008-06-10 US disclosed
US-7365077-B2 Piperazine bis-amide derivatives and their use as antagonists of the orexin receptor SMITHKLINE BEECHAM P.L.C. (GB) 2008-04-29 US disclosed
US-20080051415-A1 Novel piperazines, pharmaceutical compositions and methods of use thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH 2008-02-28 US disclosed
US-20070270434-A1 SULFONYL-SUBSTITUTED BICYCLIC COMPOUNDS AS MODULATORS OF PPAR KALYPSYS, INC. (US) 2007-11-22 US disclosed
EP-1852100-A1 METHOD FOR PRODUCING GRANULES Takeda Pharmaceutical Company Limited (JP) 2007-11-07 EP disclosed
US-20070141137-A1 Stable capsule preparation TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-06-21 US disclosed
US-20070141137-A1 Stable capsule preparation TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-06-21 US disclosed
US-7176313-B2 Anti acid-fast bacterial agent containing pyridonecarboxylic acids as active ingredient DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2007-02-13 US disclosed
US-4992150-A Telomer with alpha-olefin;oil and fuel additive NIPPON OIL CO, LTD. (JP) 1991-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230146127-A1 3-DIARYLMETHYLENES AND USES THEREOF MYC, MYCBP, FOXO1 KAT6A 1759/4885NCF1 1348/4885
US-20080138427-A1 Reduced variation in the dissolution profile of a biologically active substance; pharmaceutical, drug sprayed while spraying a binding liquid to the cores; centrifugal fluidized bed coating granulation machine set to1.5 g/cm2 SERPINA6, CMA1, CRH KAT6A 3120/4885NCF1 2903/4885
US-20230219986-A1 NOVEL AMINOPYRIMIDINE EGFR INHIBITOR EGFR, ERBB2, ERBB4 KAT6A 1854/4885NCF1 1273/4885
US-20070270434-A1 SULFONYL-SUBSTITUTED BICYCLIC COMPOUNDS AS MODULATORS OF PPAR PPARD, PPARG, PPARA KAT6A 1655/4885NCF1 3316/4885
US-20080051415-A1 Novel piperazines, pharmaceutical compositions and methods of use thereof CHRNA7, CHRNA5, CHRNA2 KAT6A 2268/4885NCF1 1867/4885
US-20070141137-A1 Stable capsule preparation PGA5, PPIA, RPS2 KAT6A 2579/4885NCF1 4423/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.