Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 10/20 | 0.51 |
| ▸ | CTSK | P43235 | 6/20 | 0.51 |
| ▸ | CTSL | P07711 | 5/20 | 0.51 |
| ▸ | CTSB | P07858 | 4/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7269917 | 0.90 | CTSL (0.57) | CTSSCTSKCTSLCTSBCASP1 | |
| SCHEMBL9011705 | 0.85 | REN (0.50) | CTSSCTSKCTSLCTSBREN | |
| SCHEMBL8372704 | 0.78 | CTSB (0.61) | CTSSCTSKCTSLCTSBCASP1 | |
| SCHEMBL6663697 | 0.77 | CTSK (0.62) | CTSSCTSKCTSLCTSBCASP1 | |
| SCHEMBL14020888 | 0.77 | CTSK (0.62) | CTSSCTSKCTSLCTSBCASP1 | |
| SCHEMBL25767336 | 0.76 | CTSL (0.63) | CTSSCTSKCTSLCTSB | |
| SCHEMBL31376823 | 0.76 | CTSS (0.58) | CTSSCTSKCTSLCTSBCASP1 | |
| SCHEMBL25285984 | 0.75 | CTSL (0.64) | CTSSCTSKCTSLCTSB | |
| SCHEMBL25285983 | 0.75 | CTSL (0.64) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6935695 | 0.75 | CTSK (0.60) | CTSSCTSKCTSLCTSBCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545750-A | TREATING HUMAN IMMUNODEFICIENCY VIRUS | ABBOTT LABORATORIES (US) | 1996-08-13 | — | — | US | disclosed |
| US-5142056-A | Human immunodeficiency virus protease inhibitor | ABBOTT LABORATORIES (US) | 1992-08-25 | — | — | US | disclosed |