SCHEMBL901173

SCHEMBL901173

O=C(O)c1ccc(C(=O)O)c(-c2ccc(O)cc2)c1-c1ccc(O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.55
CA12 O43570 3/20 0.52
CA1 P00915 3/20 0.52
CA2 P00918 3/20 0.52
CA7 P43166 3/20 0.52
CA9 Q16790 3/20 0.52
CA14 Q9ULX7 3/20 0.52
ALDH1A1 P00352 1/20 0.52
TSHR P16473 1/20 0.52
POLB P06746 2/20 0.48
TDP1 Q9NUW8 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
CA3 P07451 1/20 0.48
TYR P14679 1/20 0.48
DRD1 P21728 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48
CA5A P35218 1/20 0.48
CA5B Q9Y2D0 1/20 0.48
ALOX5 P09917 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27747520 0.81 MCL1 (0.44) HSD17B10CA12CA1CA2CA7
SCHEMBL8827317 0.81 TSHR (0.57) CA12CA1CA2CA7CA9
SCHEMBL901069 0.81 ACMSD (0.61) ALDH1A1TSHRCYP1A2HNF4AACMSD
SCHEMBL332581 0.80 ALDH1A1 (0.57) CA12CA1CA2CA7CA9
SCHEMBL8714557 0.80 HNF4A (0.59) HSD17B10ALDH1A1TDP1L3MBTL1HNF4A
SCHEMBL4946184 0.80 WDR5 (0.71) TSHRPOLBCYP1A2ESR1ESR2
SCHEMBL3399030 0.79 ALDH1A1 (0.52) HSD17B10ALDH1A1TSHRPOLBTDP1
SCHEMBL7064896 0.79 ESR1 (0.43) HSD17B10CA2ALDH1A1TSHRESR1
SCHEMBL27882502 0.79 HSD17B10 (0.53) HSD17B10CA12CA1CA2CA7
SCHEMBL28680184 0.78 HSD17B1 (0.47) HSD17B10CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0379055-B1 Mesogenic advanced epoxy compounds DOW CHEMICAL CO (US) 1999-11-10 EP claimed
EP-0573573-B1 MESOGENIC GLYCIDYL AMINES DOW CHEMICAL CO (US) 1999-09-29 EP claimed
US-5602211-A CURING AGENTS THE DOW CHEMICAL COMPANY (US) 1997-02-11 US claimed
US-5412044-A Nitro group terminated mesogenic epoxy resin adducts THE DOW CHEMICAL COMPANY (US) 1995-05-02 US claimed
US-5391651-A Curable mixtures of mesogenic epoxy resins and mesogenic polyamines and cured compositions THE DOW CHEMICAL COMPANY (US) 1995-02-21 US claimed
US-5364912-A Anisotropic melts, reaction of glycidyl ester of dicarboxylic acid and diol or dicarboxylic acid THE DOW CHEMICAL COMPANY (US) 1994-11-15 US claimed
EP-0573573-A1 MESOGENIC GLYCIDYL AMINES THE DOW CHEMICAL COMPANY (US) 1993-12-15 EP claimed
US-5270406-A Advanced epoxy resin compositions containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1993-12-14 US claimed
US-5270405-A Mesogenic epoxy compounds THE DOW CHEMICAL COMPANY (US) 1993-12-14 US claimed
US-5270404-A Curable compositions of mesogen-containing advanced epoxy resins and curing agents therefor THE DOW CHEMICAL COMPANY (US) 1993-12-14 US claimed
US-5266661-A Epoxy resins THE DOW CHEMICAL COMPANY (US) 1993-11-30 US claimed
US-5248740-A Thioepoxides, liquid crystal polymers THE DOW CHEMICAL COMPANY (US) 1993-09-28 US claimed
US-5218062-A Curable mixtures of mesogenic epoxy resins and mesogenic polyamines and cured compositions THE DOW CHEMICAL COMPANY (US) 1993-06-08 US claimed
US-5182340-A Molding materials having shorter gel time with aliphatic amine curing agents THE DOW CHEMICAL COMPANY (US) 1993-01-26 US claimed
WO-1992015630-A2 MESOGENIC GLYCIDYL AMINES THE DOW CHEMICAL COMPANY (US) 1992-09-17 WO claimed
EP-0475238-A2 Mesogenic glycidyl esters THE DOW CHEMICAL COMPANY (US) 1992-03-18 EP claimed
EP-0473935-A2 Curable mixture of mesogenic epoxy resins and mesogenic polyamines and cured compositions THE DOW CHEMICAL COMPANY (US) 1992-03-11 EP claimed
US-9340702-B2 Coating compositions BLUE CUBE IP LLC (US) 2016-05-17 US disclosed
US-4453010-A Production of hydroxy arylophenones IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-06-05 US disclosed
EP-0057503-A1 Production of hydroxy arylophenones IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-08-11 EP disclosed