Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.32 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9012178 | 0.85 | ADRA1D (0.34) | HTR1AADRA1DADRA1AADRA1BUTS2R | |
| SCHEMBL9013449 | 0.83 | UTS2R (0.33) | HTR1AADRA1DADRA1AADRA1BUTS2R | |
| SCHEMBL9011960 | 0.80 | ITK (0.30) | — | |
| SCHEMBL9011890 | 0.75 | ADRA1D (0.40) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL9329023 | 0.74 | VCP (0.32) | HTR1AADRA1DADRA1AADRA1BUTS2R | |
| SCHEMBL9012164 | 0.74 | RIPK1 (0.44) | — | |
| SCHEMBL6528639 | 0.74 | IDO1 (0.33) | ADRA1DADRA1AADRA1B | |
| SCHEMBL9329176 | 0.73 | ADRA1D (0.40) | HTR1AADRA1DADRA1AADRA1BUTS2R | |
| SCHEMBL9012300 | 0.72 | KDM4E (0.32) | UTS2R | |
| SCHEMBL9011897 | 0.72 | NPC1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523317-A | ADMINISTERING IMIDAZOLE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0633026-A1 | Use of imidazole derivative for antihypertensive agent | NIPPON CHEMIPHAR CO., LTD. (JP) | 1995-01-11 | — | — | EP | disclosed |