SCHEMBL9013659

SCHEMBL9013659

C=CS(=O)(=O)On1c(C)nc2ccccc2c1=O

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.48
ALDH1A1 P00352 2/20 0.48
LMNA P02545 1/20 0.48
GLA P06280 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
POLB P06746 2/20 0.45
CYP1A2 P05177 1/20 0.45
HSD17B10 Q99714 1/20 0.44
MAPK1 P28482 1/20 0.44
ALOX12 P18054 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14620107 0.81 KDM4E (0.51) KDM4EL3MBTL1ALDH1A1LMNACYP1A2
SCHEMBL7533236 0.81 KDM4E (0.51) KDM4EL3MBTL1ALDH1A1LMNAGLA
SCHEMBL7531474 0.80 L3MBTL1 (0.50) KDM4EL3MBTL1ALDH1A1LMNAGLA
SCHEMBL7528390 0.77 VDR (0.49) KDM4EL3MBTL1ALDH1A1LMNASMN1; SMN2
SCHEMBL14620106 0.75 KMT2A (0.51) KDM4EL3MBTL1ALDH1A1LMNASMN1; SMN2
SCHEMBL27370760 0.73 ALDH1A1 (0.66) KDM4EL3MBTL1ALDH1A1LMNACYP1A2
SCHEMBL14588659 0.70 ALDH1A1 (0.63) KDM4EL3MBTL1ALDH1A1LMNASMN1; SMN2
SCHEMBL13319273 0.70 MEN1 (0.56) KDM4EL3MBTL1ALDH1A1LMNASMN1; SMN2
SCHEMBL2731836 0.69 TDP1 (0.62) KDM4EL3MBTL1ALDH1A1LMNASMN1; SMN2
SCHEMBL2611780 0.69 KDM4E (0.50) KDM4EL3MBTL1ALDH1A1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0410606-B1 Siloxane polymers and positive working light-sensitive compositions comprising the same FUJI PHOTO FILM CO LTD (JP) 1996-11-13 EP disclosed
US-5338640-A Alkali-developable; resistance to oxygen etching; multilayer photoresists; photolithographic printing plates FUJI PHOTO FILM CO., LTD. (JP) 1994-08-16 US disclosed
US-5276124-A Ladder polymers, photoresists, lithographic printing plates FUJI PHOTO FILM CO., LTD. (JP) 1994-01-04 US disclosed
US-5252686-A Siloxane polymers and positive working light-sensitive compositions comprising the same FUJI PHOTO FILM CO., LTD. (JP) 1993-10-12 US disclosed
US-5216105-A SILICONE POLYMERS AND POSITIVE WORKING LIGHT-SENSITIVE COMPOSITIONS COMPRISING THE SAME FUJI PHOTO FILM CO., LTD. (JP) 1993-06-01 US disclosed
EP-0410606-A2 Siloxane polymers and positive working light-sensitive compositions comprising the same FUJI PHOTO FILM CO., LTD. (JP) 1991-01-30 EP disclosed