Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Methyprylon. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyprylon SCHEMBL10792726 | 0.91 | LMNA (0.38) | LMNACYP19A1 | |
| Methyprylon SCHEMBL155839 | 0.91 | LMNA (0.40) | LMNACYP19A1 | |
| Methyprylon SCHEMBL614 | 0.91 | LMNA (0.40) | LMNACYP19A1 | |
| Methyprylon SCHEMBL155838 | 0.91 | LMNA (0.40) | LMNACYP19A1 | |
| Methyprylon SCHEMBL7683591 | 0.90 | LMNA (0.34) | LMNACYP19A1 | |
| Methyprylon SCHEMBL8663851 | 0.89 | LMNA (0.33) | LMNACYP19A1 | |
| Methyprylon SCHEMBL6695974 | 0.87 | LMNA (0.34) | LMNACYP19A1 | |
| Methyprylon SCHEMBL623597 | 0.83 | LMNA (0.32) | LMNACYP19A1 | |
| Methyprylon SCHEMBL1326559 | 0.83 | LMNA (0.32) | LMNACYP19A1 | |
| Methyprylon SCHEMBL8665659 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747230-A2 | Ink-jet recording material and production method thereof | Toyo Boseki Kabushiki Kaisha (JP) | 1996-12-11 | — | — | EP | disclosed |