SCHEMBL9015250

SCHEMBL9015250

O=C(Cl)c1ccc(-c2nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.36
MEN1 O00255 4/20 0.32
KMT2A Q03164 4/20 0.32
KDM4E B2RXH2 3/20 0.32
HPGD P15428 2/20 0.32
TP53 P04637 2/20 0.32
CYP3A4 P08684 2/20 0.32
HDAC4 P56524 1/20 0.32
CYP2D6 P10635 1/20 0.32
HIF1A Q16665 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ADORA3 P0DMS8 2/20 0.31
MAP4K4 O95819 1/20 0.31
MAPT P10636 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
NPC1 O15118 1/20 0.30
PKM P14618 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
USP2 O75604 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1936088 0.85 TSHR (0.44) ALDH1A1MEN1KMT2AKDM4ETP53
SCHEMBL8412982 0.84 NPC1 (0.38) ALDH1A1MEN1KMT2AKDM4EHPGD
SCHEMBL125046 0.84 ADORA3 (0.46) ALDH1A1MEN1KMT2AKDM4EHPGD
SCHEMBL9336288 0.84 MEN1 (0.33) ALDH1A1MEN1KMT2AKDM4EHPGD
SCHEMBL7746430 0.80 MAPT (0.47) ALDH1A1MEN1KMT2AKDM4EHPGD
SCHEMBL12952337 0.80 PLK1 (0.51) MEN1KMT2AHPGDHDAC4MAPT
SCHEMBL9340148 0.80 ALDH1A1 (0.39) ALDH1A1ADORA3NPC1RAB9ASMN1; SMN2
SCHEMBL8607879 0.79 MEN1 (0.48) ALDH1A1MEN1KMT2AHPGDTP53
SCHEMBL9336331 0.77 HDAC2 (0.36) HDAC4CYP2D6MAPTCYP1A2CYP2C9
SCHEMBL9462342 0.77 HDAC2 (0.36) HDAC4CYP2D6MAPTCYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0572524-B1 RED SENSITIVE PHOTOPOLYMERIZABLE COMPOSITIONS DU PONT (US) 1996-12-18 EP disclosed
EP-0332042-B1 Aromatic compounds substituted by 4,6-bis-trichloromethyl-s-triazin-2-yl groups, process for their preparation and their use in photosensitive mixtures HOECHST AG (DE) 1994-05-25 EP disclosed
EP-0332043-B1 Oxadiazole derivatives containing 4,6-bis-trichloromethyl-s-triazin-2-yl groups, process for their preparation and photosensitive mixture containing them HOECHST AG (DE) 1994-05-18 EP disclosed
EP-0572524-A1 RED SENSITIVE PHOTOPOLYMERIZABLE COMPOSITIONS. DU PONT (US) 1993-12-08 EP disclosed
EP-0332044-B1 HETEROCYCLIC COMPOUNDS CONTAINING 4,6-BIS-TRICHLOROMETHYL-S-TRIAZIN-2-YL GROUPS, PROCESS FOR THEIR PREPARATION AND PHOTOSENSITIVE MIXTURE CONTAINING THEM HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-16 EP disclosed
US-5216158-A Oxadiazole compounds containing 4,6-bis-trichloromethyl-S-triazin-2-yl groups, process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-01 US disclosed
US-5147758-A Containing squarylium dye, boron anion initiator E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-09-15 US disclosed
WO-1992014765-A1 RED SENSITIVE PHOTOPOLYMERIZABLE COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-09-03 WO disclosed
US-5064959-A Photoinitiators HOECHST AKTIENGESELLSCHAFT (DE) 1991-11-12 US disclosed
US-5055579-A Photoinitiators; high sensitivity in visible spectral range; stability HOECHST AKTIENGESELLSCHAFT (DE) 1991-10-08 US disclosed
EP-0332043-A1 Oxadiazole derivatives containing 4,6-bis-trichloromethyl-s-triazin-2-yl groups, process for their preparation and photosensitive mixture containing them HOECHST AKTIENGESELLSCHAFT (DE) 1989-09-13 EP disclosed
EP-0332044-A1 Heterocyclic compounds containing 4,6-bis-trichloromethyl-s-triazin-2-yl groups, process for their preparation and photosensitive mixture containing them HOECHST AKTIENGESELLSCHAFT (DE) 1989-09-13 EP disclosed
EP-0332042-A1 Aromatic compounds substituted by 4,6-bis-trichloromethyl-s-triazin-2-yl groups, process for their preparation and their use in photosensitive mixtures HOECHST AKTIENGESELLSCHAFT (DE) 1989-09-13 EP disclosed