Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 3/20 | 0.43 |
| ▸ | RXRB | P28702 | 3/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | BAD | Q92934 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RXRG | P48443 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9015250 | 0.85 | ALDH1A1 (0.36) | TP53KDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL8412982 | 0.84 | NPC1 (0.38) | TSHRKDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL125046 | 0.84 | ADORA3 (0.46) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9336288 | 0.84 | MEN1 (0.33) | TP53KDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL13901177 | 0.81 | ALOX15 (0.41) | TSHRTP53ALOX15KDM4EALDH1A1 | |
| SCHEMBL12952337 | 0.80 | PLK1 (0.51) | TSHRRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL14138137 | 0.80 | ABCC4 (0.49) | TSHRRXRARXRBRXRGGAA | |
| SCHEMBL7746430 | 0.80 | MAPT (0.47) | TSHRTP53KDM4EALDH1A1RAB9A | |
| SCHEMBL9874042 | 0.80 | KMO (0.51) | RXRARXRBKDM4EALDH1A1RAB9A | |
| SCHEMBL1975452 | 0.80 | TSHR (0.63) | TSHRTP53RXRARXRBBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114949368-B | Fiber-hydrogel composite surgical mesh for tissue repair | 约翰·霍普金斯大学 | 2024-09-20 | — | — | CN | disclosed |
| CN-108289734-B | Mesenchymal cell binding composite for tissue recovery | 约翰·霍普金斯大学 | 2024-06-18 | — | — | CN | disclosed |
| WO-2024073758-A1 | NANOFIBER-HYDROGEL COMPOSITES AND METHODS FOR INHIBITING ADHESION FORMATION | THE JOHNS HOPKINS UNIVERSITY (US) | 2024-04-04 | — | — | WO | disclosed |
| EP-4090262-A1 | COMPOSITE MATERIALS AND EMBOLIZATION METHODS | The Johns Hopkins University (US) | 2022-11-23 | — | — | EP | disclosed |
| CN-114949368-A | Fiber-hydrogel composite surgical mesh for tissue repair | 约翰·霍普金斯大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-108601644-B | Fiber-hydrogel composite surgical mesh for tissue repair | 约翰·霍普金斯大学 | 2022-04-22 | — | — | CN | disclosed |
| US-9809713-B2 | Photoactivatable crosslinker compositions for surface modification | INNOVATION SURFACE TECHNOLOGIES, INC. (US) | 2017-11-07 | — | — | US | disclosed |
| US-8815259-B2 | Drug eluting superhydrophobic coatings | INNOVATIVE SURFACE TECHNOLOGIES, INC. (US) | 2014-08-26 | — | — | US | disclosed |
| US-20110223212-A1 | DRUG ELUTING SUPERHYDROPHOBIC COATINGS | Innovative Surface Technologies Inc. | 2011-09-15 | — | — | US | disclosed |
| US-20110223336-A1 | PHOTOACTIVATABLE CROSSLINKER COMPOSITIONS FOR SURFACE MODIFICATION | INNOVATIVE SURFACE TECHNOLOGIES, INC. (US) | 2011-09-15 | — | — | US | disclosed |
| EP-2344212-A1 | DRUG ELUTING SUPERHYDROPHOBIC COATINGS | Innovative Surface Technologies, Inc. (US) | 2011-07-20 | — | — | EP | disclosed |
| EP-2331644-A1 | PHOTOACTIVATABLE CROSSLINKER COMPOSITIONS FOR SURFACE MODIFICATION | Innovative Surface Technologies, Inc. (US) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010033482-A1 | DRUG ELUTING SUPERHYDROPHOBIC COATINGS | INNOVATIVE SURFACE TECHNOLOGIES, INC. (US) | 2010-03-25 | — | — | WO | disclosed |
| WO-2010028104-A1 | PHOTOACTIVATABLE CROSSLINKER COMPOSITIONS FOR SURFACE MODIFICATION | INNOVATIVE SURFACE TECHNOLOGIES, INC. (US) | 2010-03-11 | — | — | WO | disclosed |
| EP-1788429-B1 | Method of making a lithographic printing plate | AGFA GRAPHICS NV (BE) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007057346-A2 | METHOD OF MAKING A LITHOGRAPHIC PRINTING PLATE | AGFA GRAPHICS NV (BE) | 2007-05-24 | — | — | WO | disclosed |
| EP-1788429-A1 | Method of making a lithographic printing plate | Agfa Graphics N.V. (BE) | 2007-05-23 | — | — | EP | disclosed |
| US-5216158-A | Oxadiazole compounds containing 4,6-bis-trichloromethyl-S-triazin-2-yl groups, process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-01 | — | — | US | disclosed |
| US-5064959-A | Photoinitiators | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-12 | — | — | US | disclosed |
| US-5055579-A | Photoinitiators; high sensitivity in visible spectral range; stability | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110223212-A1 | DRUG ELUTING SUPERHYDROPHOBIC COATINGS | ABCB11, ABCB1, VEGFA | TSHR 4090/4885TP53 2544/4885RXRA 3099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.