Octocrylene

Octocrylene

SCHEMBL9015793

CCCCC(CC)COC(=O)C(C#N)=C(c1ccccc1)c1ccccc1.CCCCC(CC)COc1ccccc1C(=O)O

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.79
LMNA P02545 3/20 0.79
MAPK1 P28482 3/20 0.79
CYP3A4 P08684 3/20 0.49
CA2 P00918 1/20 0.49
PRSS1 P07477 1/20 0.45
PRSS2 P07478 1/20 0.45
PRSS3 P35030 1/20 0.45
TSHR P16473 3/20 0.41
KMT2A Q03164 2/20 0.40
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 1/20 0.40
RECQL P46063 1/20 0.40
HSD17B10 Q99714 1/20 0.39
ABCB1 P08183 2/20 0.37
TDP1 Q9NUW8 2/20 0.36
ATM Q13315 1/20 0.36
LTB4R Q15722 1/20 0.35
LTB4R2 Q9NPC1 1/20 0.35
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Octocrylene SCHEMBL16483 0.89 ALDH1A1 (1.00) ALDH1A1LMNAMAPK1CYP3A4CA2
Octocrylene SCHEMBL1769135 0.89 ALDH1A1 (1.00) ALDH1A1LMNAMAPK1CYP3A4CA2
Octocrylene SCHEMBL3216088 0.89 ALDH1A1 (0.82) ALDH1A1LMNAMAPK1CYP3A4CA2
Octocrylene SCHEMBL28123035 0.88 ALDH1A1 (0.98) ALDH1A1LMNAMAPK1CYP3A4CA2
Octocrylene SCHEMBL19583477 0.87 ALDH1A1 (0.95) ALDH1A1LMNAMAPK1CYP3A4CA2
Octocrylene SCHEMBL818975 0.86 ALDH1A1 (0.93) ALDH1A1LMNAMAPK1CYP3A4CA2
Octocrylene SCHEMBL8180706 0.86 ALDH1A1 (0.93) ALDH1A1LMNAMAPK1CYP3A4CA2
SCHEMBL13492185 0.86 ALDH1A1 (0.93) ALDH1A1LMNAMAPK1CYP3A4CA2
SCHEMBL9015799 0.85 ALDH1A1 (0.57) ALDH1A1LMNAMAPK1CYP3A4CA2
SCHEMBL9069195 0.85 ALDH1A1 (0.88) ALDH1A1LMNAMAPK1CYP3A4CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11766397-B2 Bioactive compositions comprising ficus serum fracton and methods to reduce the appearance of skin hyperpigmentation ISP INVESTMENTS LLC (US) 2023-09-26 US disclosed
EP-0747038-A2 Thickened and stabilized cosmetic sunscreen emulsions UNILEVER PLC (GB) 1996-12-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11766397-B2 Bioactive compositions comprising ficus serum fracton and methods to reduce the appearance of skin hyperpigmentation CUTA, FIBP, FGF23 ALDH1A1 3028/4885LMNA 1749/4885MAPK1 752/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.