Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL403831 | 0.85 | L3MBTL1 (0.38) | CTNNB1TTRSTK39KDM4EHSD17B10 | |
| SCHEMBL10708885 | 0.81 | FABP4 (0.38) | BRD4FABP4CYP1A2SMN1; SMN2 | |
| SCHEMBL500126 | 0.81 | KDM4E (0.45) | SRCKDM4EHSD17B10FABP4 | |
| Phosphoric Acid SCHEMBL133555 | 0.80 | L3MBTL1 (0.41) | KDM4EHSD17B10SMN1; SMN2NPSR1L3MBTL1 | |
| SCHEMBL22199023 | 0.78 | LTA4H (0.39) | TTRBRD4CYP1A2CYP2C9CYP2C19 | |
| Phosphoric Acid SCHEMBL5679958 | 0.77 | GPR84 (0.41) | CTNNB1TTRSRCADORA2A | |
| Phosphoric Acid SCHEMBL4371348 | 0.77 | GPR84 (0.41) | CTNNB1TTRSRCADORA2A | |
| Phosphoric Acid SCHEMBL3937323 | 0.76 | MMP2 (0.38) | CYP2C9NPSR1L3MBTL1 | |
| SCHEMBL11749957 | 0.76 | ALDH1A1 (0.45) | CTNNB1BRD4CYP1A2CYP2C9CYP2C19 | |
| Phosphoric Acid SCHEMBL9017459 | 0.76 | GAPDH (0.42) | CTNNB1TTRSRCKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0136924-B1 | SILVER HALIDE LIGHT-SENSITIVE COLOUR PHOTOGRAPHIC MATERIAL | KONICA CORPORATION (JP) | 1987-09-23 | — | — | EP | disclosed |
| US-4576909-A | Silver halide color photographic light-sensitive material | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1986-03-18 | — | — | US | disclosed |
| EP-0136924-A2 | Silver halide light-sensitive colour photographic material | KONICA CORPORATION (JP) | 1985-04-10 | — | — | EP | disclosed |