Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023944 | 0.88 | KDM4E (0.46) | L3MBTL1PARP1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL9025023 | 0.86 | L3MBTL1 (0.50) | L3MBTL1PARP1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL9024575 | 0.83 | NQO2 (0.36) | HPGD | |
| SCHEMBL9024667 | 0.81 | NQO1 (0.39) | KDM4EALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL9739130 | 0.80 | NQO2 (0.46) | PARP1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL9024406 | 0.76 | KMT2A (0.39) | L3MBTL1PARP1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL9023847 | 0.72 | G6PD (0.39) | HPGDHTTMAPT | |
| SCHEMBL9024703 | 0.71 | NQO2 (0.48) | — | |
| SCHEMBL9024299 | 0.70 | NQO2 (0.49) | — | |
| SCHEMBL9023722 | 0.70 | TOP2A (0.38) | L3MBTL1PARP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347749-B1 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO KK (JP) | 1996-04-24 | — | — | EP | disclosed |