Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023606 | 0.88 | ALDH1A1 (0.34) | PARP1NQO2MAOAABCG2L3MBTL1 | |
| SCHEMBL9024529 | 0.85 | KDM1A (0.34) | KDM1APARP1NQO1NQO2MAOA | |
| SCHEMBL9024129 | 0.84 | ABCB1 (0.36) | KDM1APARP1NQO1NQO2MAOA | |
| SCHEMBL9025389 | 0.83 | KDM1A (0.41) | KDM1APARP1NQO1NQO2MAOA | |
| SCHEMBL9023936 | 0.83 | NQO2 (0.34) | PARP1NQO1NQO2P2RX4 | |
| SCHEMBL9023722 | 0.82 | TOP2A (0.38) | KDM1APARP1NQO1NQO2L3MBTL1 | |
| SCHEMBL9023550 | 0.81 | G6PD (0.46) | PARP1NQO1NQO2MAOAMEN1 | |
| SCHEMBL9024132 | 0.81 | ALDH1A1 (0.33) | PARP1MAOAABCG2L3MBTL1KCNA3 | |
| SCHEMBL9025088 | 0.78 | ALDH1A1 (0.40) | PARP1NQO1NQO2KCNA3P2RX4 | |
| SCHEMBL9023281 | 0.73 | KMT2A (0.36) | NQO2MEN1KMT2APABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347749-B1 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO KK (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5079358-A | Humans; leukemia | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-01-07 | — | — | US | disclosed |