Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NQO1 | P15559 | 2/20 | 0.35 |
| ▸ | NQO2 | P16083 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024823 | 0.89 | P2RX4 (0.36) | ABCB1KDM4ENQO1NQO2GLA | |
| SCHEMBL9025049 | 0.85 | G6PD (0.47) | ABCB1KDM4ETSHRNQO1NQO2 | |
| SCHEMBL9024129 | 0.81 | ABCB1 (0.36) | ABCB1NQO1NQO2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9025088 | 0.80 | ALDH1A1 (0.40) | KDM4ENQO1NQO2GLAP2RX4 | |
| SCHEMBL2725699 | 0.78 | NQO1 (0.39) | KDM4ETSHRNQO1NQO2GLA | |
| SCHEMBL9023281 | 0.74 | KMT2A (0.36) | ABCB1KDM4ENQO2GLAALDH1A1 | |
| SCHEMBL9738372 | 0.72 | NQO2 (0.46) | KDM4ENQO1NQO2ALDH1A1 | |
| SCHEMBL9023557 | 0.72 | MEN1 (0.34) | SMN1; SMN2 | |
| SCHEMBL9024529 | 0.71 | KDM1A (0.34) | NQO1NQO2P2RX4ALDH1A1G6PD | |
| SCHEMBL9036810 | 0.70 | NQO2 (0.36) | NQO1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347749-B1 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO KK (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5079358-A | Humans; leukemia | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-01-07 | — | — | US | disclosed |
| EP-0347749-A2 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1989-12-27 | — | — | EP | disclosed |