Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 6/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024977 | 0.84 | SIGMAR1 (0.35) | SLC6A9POLB | |
| SCHEMBL9205301 | 0.84 | EGLN1 (0.40) | SLC6A9POLBEGLN1 | |
| SCHEMBL30764646 | 0.82 | NPC1 (0.35) | SLC6A9POLB | |
| SCHEMBL1394889 | 0.82 | SLC6A9 (0.42) | SLC6A9POLBEGLN1 | |
| SCHEMBL9269191 | 0.82 | KMT2A (0.39) | SCN9A | |
| SCHEMBL9305546 | 0.81 | ALDH1A1 (0.33) | SLC6A9POLBSCN9AEGLN1 | |
| SCHEMBL16021612 | 0.80 | SLC6A9 (0.44) | SLC6A9 | |
| SCHEMBL7869921 | 0.78 | EGLN1 (0.39) | SLC6A9POLBEGLN1 | |
| SCHEMBL20624199 | 0.78 | EGLN1 (0.36) | SLC6A9POLBEGLN1 | |
| SCHEMBL23975536 | 0.78 | SLC6A9 (0.36) | SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5403572-A | Macrocyclic polyaza compounds containing 5 or 6 membered rings, process for producing them and pharmaceutical media containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-04-04 | — | — | US | disclosed |
| US-5334371-A | Marcocyclic polyaza bicyclo compounds containing 5 or 6 membered rings, and method for MRI | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-08-02 | — | — | US | disclosed |