Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.35 |
| ▸ | PAICS | P22234 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | MELK | Q14680 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9061947 | 0.85 | S1PR1 (0.42) | DRD2DRD4DRD3HTR7 | |
| SCHEMBL9025516 | 0.85 | PDE7A (0.37) | KDM4EL3MBTL1KCNH2SCN9APAICS | |
| SCHEMBL9220071 | 0.82 | MEN1 (0.44) | ACHEHTR7 | |
| SCHEMBL9030860 | 0.82 | KDM4E (0.39) | KDM4EL3MBTL1ALDH1A1LMNAMAPK1 | |
| SCHEMBL9025554 | 0.78 | MAPK14 (0.39) | MAPK14KDM4EL3MBTL1KCNH2ABCB1 | |
| SCHEMBL9026336 | 0.78 | CYP11B2 (0.47) | KDM4EABCB1ALDH1A1MAPK1MAPT | |
| SCHEMBL9032018 | 0.76 | DHFR (0.39) | KDM4EABCB1ALDH1A1LMNAMAPT | |
| SCHEMBL9026132 | 0.76 | HRH3 (0.49) | KDM4EKCNH2ALDH1A1DRD3MAPT | |
| SCHEMBL9025657 | 0.75 | MAPK14 (0.37) | MAPK14KDM4EL3MBTL1KCNH2ABCB1 | |
| SCHEMBL9025514 | 0.75 | PDE4A (0.39) | KDM4EL3MBTL1ABCB1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711290-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1996-05-15 | — | — | EP | disclosed |