Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9061947 | 0.91 | S1PR1 (0.42) | MEN1KMT2AHTR7 | |
| SCHEMBL9030860 | 0.83 | KDM4E (0.39) | — | |
| SCHEMBL9025565 | 0.82 | MAPK14 (0.39) | HTR7ACHE | |
| SCHEMBL9025516 | 0.81 | PDE7A (0.37) | — | |
| SCHEMBL9026132 | 0.81 | HRH3 (0.49) | KMT2APOLB | |
| SCHEMBL9026859 | 0.78 | ADRA2A (0.45) | MEN1KMT2AACHEPOLBNPC1 | |
| SCHEMBL9025520 | 0.78 | METAP2 (0.38) | MEN1KMT2AACHEPOLB | |
| SCHEMBL9025089 | 0.78 | KDM4E (0.41) | MEN1KMT2ATP53NPC1RAB9A | |
| SCHEMBL9026950 | 0.78 | HTR1A (0.51) | — | |
| SCHEMBL9026008 | 0.77 | PKM (0.38) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995004052-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1995-02-09 | — | — | WO | disclosed |