Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026859 | 0.90 | ADRA2A (0.45) | NQO1ADRA2AADRA1ACYP2D6MAPT | |
| SCHEMBL9025520 | 0.83 | METAP2 (0.38) | NQO1MAPTMEN1KMT2AGPR84 | |
| SCHEMBL9025089 | 0.83 | KDM4E (0.41) | NQO1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL9026008 | 0.82 | PKM (0.38) | NQO1MAPTGPR84 | |
| SCHEMBL9216019 | 0.82 | NQO1 (0.36) | NQO1MAPTGPR84 | |
| SCHEMBL9024896 | 0.82 | MYB (0.36) | NQO1MAPTMEN1KMT2AGPR84 | |
| SCHEMBL9025436 | 0.79 | TSHR (0.39) | MEN1KMT2AMAPK1GPR84HCRTR1 | |
| SCHEMBL9026458 | 0.76 | KDM4E (0.41) | LTA4HADRA2AADRA1ACYP2D6MAPT | |
| SCHEMBL9025514 | 0.76 | PDE4A (0.39) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL9026660 | 0.75 | MAPT (0.35) | NQO1MAPTMEN1KMT2AGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711290-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004052-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1995-02-09 | — | — | WO | disclosed |