Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 4/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025568 | 0.80 | METAP2 (0.39) | LPAR1SLC6A2SLC6A4ALDH1A1POLB | |
| SCHEMBL9026705 | 0.77 | SLC6A2 (0.37) | LPAR1SLC6A2SLC6A4ALDH1A1POLB | |
| SCHEMBL9026962 | 0.77 | LPAR1 (0.37) | LPAR1SLC6A2SLC6A4SLC9A1ALDH1A1 | |
| SCHEMBL9025682 | 0.77 | HTR2C (0.36) | SLC9A1POLBMAPTSMN1; SMN2NPC1 | |
| SCHEMBL9025817 | 0.75 | LPAR1 (0.36) | LPAR1SLC6A2SLC6A4ALDH1A1HPGD | |
| SCHEMBL9026968 | 0.75 | HTT (0.38) | LPAR1ALDH1A1POLBMAPTSMN1; SMN2 | |
| SCHEMBL9025107 | 0.74 | OPRK1 (0.35) | ALDH1A1HPGDPOLBGAAMAPT | |
| SCHEMBL9024534 | 0.74 | POLB (0.32) | SLC6A2SLC6A4ALDH1A1HPGDPOLB | |
| SCHEMBL9027103 | 0.74 | ACHE (0.35) | LPAR1SLC6A2SLC6A4ALDH1A1MAPT | |
| SCHEMBL9032014 | 0.71 | MAPT (0.36) | SLC6A4SLC9A1POLBMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711290-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004052-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1995-02-09 | — | — | WO | disclosed |