Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026705 | 0.89 | SLC6A2 (0.37) | ACHELPAR1TDP1L3MBTL1NPC1 | |
| SCHEMBL9025767 | 0.85 | SLC9A1 (0.37) | TDP1L3MBTL1NPC1RAB9ANPSR1 | |
| SCHEMBL9025568 | 0.83 | METAP2 (0.39) | ACHELPAR1TDP1L3MBTL1NPC1 | |
| SCHEMBL9025817 | 0.83 | LPAR1 (0.36) | ACHELPAR1TDP1L3MBTL1NPC1 | |
| SCHEMBL9024534 | 0.81 | POLB (0.32) | TDP1L3MBTL1NPC1RAB9ANPSR1 | |
| SCHEMBL9027093 | 0.76 | LMNA (0.36) | ACHELPAR1NPC1RAB9AMAPT | |
| SCHEMBL9025682 | 0.75 | HTR2C (0.36) | L3MBTL1NPC1MAPTKMT2AMEN1 | |
| SCHEMBL9026972 | 0.74 | LPAR1 (0.35) | LPAR1NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL9025107 | 0.73 | OPRK1 (0.35) | L3MBTL1NPC1MAPTKMT2AMEN1 | |
| SCHEMBL9032014 | 0.71 | MAPT (0.36) | NPC1MAPTKMT2AMEN1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711290-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004052-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1995-02-09 | — | — | WO | disclosed |