Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 3/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025568 | 0.85 | METAP2 (0.39) | LPAR1ACHENPC1TDP1L3MBTL1 | |
| SCHEMBL9027103 | 0.83 | ACHE (0.35) | LPAR1ACHEDPP4NPC1TDP1 | |
| SCHEMBL9025806 | 0.78 | MAPT (0.39) | LPAR1NPC1MAPTRAB9AKMT2A | |
| SCHEMBL9026705 | 0.77 | SLC6A2 (0.37) | LPAR1CRHR1ACHENPC1TDP1 | |
| SCHEMBL9025682 | 0.77 | HTR2C (0.36) | NPC1L3MBTL1MAPTKMT2AMEN1 | |
| SCHEMBL9026972 | 0.75 | LPAR1 (0.35) | LPAR1NPC1MAPTRAB9ASLC6A2 | |
| SCHEMBL9025107 | 0.74 | OPRK1 (0.35) | NPC1L3MBTL1MAPTKMT2AMEN1 | |
| SCHEMBL9024534 | 0.74 | POLB (0.32) | CRHR1NPC1TDP1L3MBTL1RAB9A | |
| SCHEMBL9025767 | 0.74 | SLC9A1 (0.37) | NPC1TDP1L3MBTL1MAPTRAB9A | |
| SCHEMBL9026040 | 0.73 | HTR2C (0.39) | MAPTSLC6A2SLC6A4KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711290-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004052-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1995-02-09 | — | — | WO | disclosed |