Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PPIA | P62937 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL899322 | 0.89 | OPRD1 (0.35) | F2RL3SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL899483 | 0.85 | PTGS2 (0.36) | SMN1; SMN2ALDH1A1MAPTLMNANPC1 | |
| SCHEMBL898805 | 0.84 | GRM5 (0.34) | SMN1; SMN2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL898806 | 0.84 | GRM5 (0.34) | SMN1; SMN2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL7096459 | 0.73 | MEN1 (0.50) | F2RL3TSHRSMN1; SMN2RECQLMAPK10 | |
| SCHEMBL7096458 | 0.73 | MEN1 (0.50) | F2RL3TSHRSMN1; SMN2RECQLMAPK10 | |
| SCHEMBL10045068 | 0.72 | ALDH1A1 (0.52) | F2RL3TSHRSMN1; SMN2RECQLMAPK10 | |
| SCHEMBL899220 | 0.70 | PDE4D (0.38) | TSHRSMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL899218 | 0.70 | PDE4D (0.38) | TSHRSMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL18255821 | 0.70 | MKNK1 (0.50) | TSHRSMN1; SMN2ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040754-A2 | NOVEL THIAZOLAMINE DERIVATES AS DIFFERENTIATION ACCELERATORS | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2012-04-05 | — | — | WO | disclosed |