Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 6/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GNRHR | P30968 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL903008 | 0.89 | F2RL3 (0.44) | MEN1KMT2AF2RL3LMNAALDH1A1 | |
| SCHEMBL899483 | 0.85 | PTGS2 (0.36) | LMNAALDH1A1MAPTKDM4ENPC1 | |
| SCHEMBL898805 | 0.83 | GRM5 (0.34) | ALDH1A1MAPTNPSR1MAPK1KDM4E | |
| SCHEMBL898806 | 0.83 | GRM5 (0.34) | ALDH1A1MAPTNPSR1MAPK1KDM4E | |
| SCHEMBL899218 | 0.70 | PDE4D (0.38) | ALDH1A1MAPTNPSR1MAPK1CRHBP | |
| SCHEMBL899220 | 0.70 | PDE4D (0.38) | ALDH1A1MAPTNPSR1MAPK1CRHBP | |
| SCHEMBL2570512 | 0.68 | OPRD1 (0.54) | OPRD1OPRK1OPRM1LMNAALDH1A1 | |
| SCHEMBL899307 | 0.65 | MAPT (0.46) | LMNAALDH1A1MAPTNPSR1MAPK1 | |
| SCHEMBL899306 | 0.65 | MAPT (0.46) | LMNAALDH1A1MAPTNPSR1MAPK1 | |
| SCHEMBL898781 | 0.65 | ROCK2 (0.41) | LMNANPSR1MAPK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040754-A2 | NOVEL THIAZOLAMINE DERIVATES AS DIFFERENTIATION ACCELERATORS | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2012-04-05 | — | — | WO | claimed |
| WO-2012040754-A2 | NOVEL THIAZOLAMINE DERIVATES AS DIFFERENTIATION ACCELERATORS | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2012-04-05 | — | — | WO | disclosed |