Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BDKRB1 | P46663 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8906160 | 0.86 | POLB (0.44) | KMT2AALDH1A1AKR1B1HTTL3MBTL1 | |
| SCHEMBL8904850 | 0.83 | ALDH1A1 (0.40) | KMT2AALDH1A1AKR1B1HTTL3MBTL1 | |
| SCHEMBL8905531 | 0.80 | CYP3A4 (0.43) | KMT2AALDH1A1AKR1B1POLBLMNA | |
| SCHEMBL8904327 | 0.78 | RAB9A (0.35) | KMT2AALDH1A1LMNAF2MAPT | |
| SCHEMBL9030270 | 0.78 | PDE3B (0.42) | KMT2AALDH1A1HTTL3MBTL1LMNA | |
| SCHEMBL8905805 | 0.77 | LMNA (0.38) | KMT2AALDH1A1AKR1B1HTTL3MBTL1 | |
| SCHEMBL9030473 | 0.77 | PKM (0.36) | KMT2AALDH1A1HTTL3MBTL1POLB | |
| SCHEMBL8905938 | 0.76 | MEN1 (0.38) | KMT2AALDH1A1AKR1B1HTTL3MBTL1 | |
| SCHEMBL8904194 | 0.76 | CCNA2 (0.38) | KMT2AALDH1A1AKR1B1HTTL3MBTL1 | |
| SCHEMBL8904574 | 0.74 | NPC1 (0.42) | KMT2AALDH1A1HTTL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714895-A1 | Pyrrole derivatives | F. Hoffmann-La Roche AG (CH) | 1996-06-05 | — | — | EP | disclosed |