Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050939 | 0.82 | GHSR (0.39) | ATMMEN1KMT2AGHSRLMNA | |
| SCHEMBL9033444 | 0.77 | MAOA (0.41) | ATMPTGESMEN1KMT2AMAOA | |
| SCHEMBL9034245 | 0.75 | L3MBTL1 (0.35) | KMT2A | |
| SCHEMBL9033473 | 0.65 | ANPEP (0.47) | MEN1KMT2A | |
| SCHEMBL9033517 | 0.65 | POLB (0.40) | MEN1KMT2ACTSDCYP2D6CYP2C9 | |
| SCHEMBL9033512 | 0.65 | POLB (0.46) | MEN1KMT2ACYP2D6CYP2C9 | |
| SCHEMBL18216887 | 0.64 | LMNA (0.56) | PTGESMEN1KMT2ALMNA | |
| SCHEMBL25233983 | 0.63 | CTSL (0.43) | PTGESMEN1KMT2ALMNA | |
| SCHEMBL25233981 | 0.63 | CTSL (0.43) | PTGESMEN1KMT2ALMNA | |
| SCHEMBL9034247 | 0.62 | DPP4 (0.38) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696593-A2 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-02-14 | — | — | EP | claimed |
| EP-0696593-A2 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-02-14 | — | — | EP | disclosed |