Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9033814 | 0.92 | LMNA (0.37) | ALDH1A1LMNAMAPK1TSHRMAPT | |
| SCHEMBL9033537 | 0.81 | L3MBTL1 (0.32) | L3MBTL1 | |
| SCHEMBL9032688 | 0.80 | L3MBTL1 (0.33) | L3MBTL1 | |
| SCHEMBL9033517 | 0.79 | POLB (0.40) | TSHR | |
| SCHEMBL9033533 | 0.77 | HPGD (0.31) | HPGD | |
| SCHEMBL9033478 | 0.75 | ANPEP (0.44) | ALDH1A1 | |
| SCHEMBL9032679 | 0.75 | L3MBTL1 (0.31) | L3MBTL1 | |
| SCHEMBL9032567 | 0.75 | GPR88 (0.32) | L3MBTL1 | |
| SCHEMBL9033807 | 0.74 | DPP4 (0.35) | — | |
| SCHEMBL9033512 | 0.73 | POLB (0.46) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696593-A2 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-02-14 | — | — | EP | disclosed |