Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.58 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | DHFR | P00374 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ALB | P02768 | 1/20 | 0.58 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13652987 | 0.85 | TTR (0.60) | TTRACMSDKDM4EMEN1USP2 | |
| SCHEMBL1906156 | 0.81 | KLF10 (0.50) | HIF1AKLF10CA3CA6CA5A | |
| SCHEMBL412535 | 0.77 | ESR1 (0.55) | TTRACMSDKDM4EMEN1USP2 | |
| SCHEMBL13652985 | 0.77 | TTR (0.59) | TTRACMSDKDM4EMEN1USP2 | |
| SCHEMBL13652988 | 0.77 | ALDH1A1 (0.59) | TTRACMSDKDM4EMEN1USP2 | |
| SCHEMBL2760398 | 0.77 | TTR (0.59) | TTRACMSDKDM4EMEN1USP2 | |
| SCHEMBL14408194 | 0.77 | TTR (0.59) | TTRACMSDKDM4EMEN1USP2 | |
| SCHEMBL9057929 | 0.77 | ALDH1A1 (0.52) | TTRACMSDKDM4EMEN1USP2 | |
| SCHEMBL9418406 | 0.77 | GABRA1 (0.56) | HIF1AKLF10APPHSD17B1PKM | |
| SCHEMBL19321459 | 0.74 | MEN1 (0.49) | TTRACMSDKDM4EMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210169905-A1 | FATTY ACID ACETYLATED SALICYLATES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. | 2021-06-10 | — | — | US | disclosed |
| US-20200046738-A1 | FATTY ACID ACETYLATED SALICYLATES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. | 2020-02-13 | — | — | US | disclosed |
| US-10358452-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and uses thereof | KEMPHARM, INC. (US) | 2019-07-23 | — | — | US | disclosed |
| US-20170246193-A1 | FATTY ACID ACETYLATED SALICYLATES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. | 2017-08-31 | — | — | US | disclosed |
| US-20170143696-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROCODONE, PRODRUGS, METHODS OF MAKING AND USES THEREOF | ALTER DOMUS (US) LLC | 2017-05-25 | — | — | US | disclosed |
| EP-0537313-B1 | ARYLALKYL ESTERS OF 4,5-DIHYDROXY-9,10-DIHYDRO-9,10-DIOXO-2-ANTHRACENECARBOXYLIC ACID HAVING THERAPEUTICAL ACTIVITY | GENTILI IST SPA (IT) | 1996-01-17 | — | — | EP | disclosed |
| US-5330981-A | Antiinflammatory agents | ISTITUTO GENTILI S.P.A. (IT) | 1994-07-19 | — | — | US | disclosed |
| EP-0537313-A1 | ARYLALKYL ESTERS OF 4,5-DIHYDROXY-9,10-DIHYDRO-9,10-DIOXO-2-ANTHRACENECARBOXYLIC ACID HAVING THERAPEUTICAL ACTIVITY. | GENTILI IST SPA (IT) | 1993-04-21 | — | — | EP | disclosed |
| EP-0254354-B1 | PHARMACEUTICALLY USEFUL DERIVATIVES OF THIAZOLIDINE-4-CARBOXYLIC ACID | ZAMBON S.p.A. (IT) | 1993-03-31 | — | — | EP | disclosed |
| WO-1992019584-A1 | ARYLALKYL ESTERS OF 4,5-DIHYDROXY-9,10-DIHYDRO-9,10-DIOXO-2-ANTHRACENECARBOXYLIC ACID HAVING THERAPEUTICAL ACTIVITY | ISTITUTO GENTILI S.P.A. (IT) | 1992-11-12 | — | — | WO | disclosed |
| US-4840936-A | ANTIFLAMMATORY, ANALGESIC AGENT TO PREVENT ARRHYTHMIAS | ZAMBON S.P.A. (IT) | 1989-06-20 | — | — | US | disclosed |
| EP-0254354-A1 | Pharmaceutically useful derivatives of thiazolidine-4-carboxylic acid | ZAMBON S.p.A. (IT) | 1988-01-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200046738-A1 | FATTY ACID ACETYLATED SALICYLATES AND THEIR USES | FASN, ACACA, FABP4 | TTR 3296/4885ACMSD 585/4885KDM4E 2493/4885 |
| US-20170143696-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROCODONE, PRODRUGS, METHODS OF MAKING AND USES THEREOF | CYP2B6, CYP3A43, CYP2D6 | TTR 2568/4885ACMSD 264/4885KDM4E 1814/4885 |
| US-10358452-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and uses thereof | CYP2B6, CYP3A43, CYP2D6 | TTR 2568/4885ACMSD 264/4885KDM4E 1814/4885 |
| US-20170246193-A1 | FATTY ACID ACETYLATED SALICYLATES AND THEIR USES | FASN, ACACA, FABP4 | TTR 3296/4885ACMSD 585/4885KDM4E 2493/4885 |
| US-20210169905-A1 | FATTY ACID ACETYLATED SALICYLATES AND THEIR USES | FASN, ACACA, FABP4 | TTR 3296/4885ACMSD 585/4885KDM4E 2493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.