Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904332 | 0.81 | SLC6A2 (0.46) | DRD1HTR2AKDM4EALDH1A1HPGD | |
| SCHEMBL904323 | 0.76 | DRD2 (0.39) | DRD1TP53 | |
| SCHEMBL904324 | 0.71 | CA1 (0.50) | DRD1HTR2AKDM4EALDH1A1LMNA | |
| SCHEMBL1986595 | 0.67 | ALOX5 (0.49) | — | |
| SCHEMBL1989261 | 0.65 | ALOX5 (0.53) | DRD1KDM4E | |
| SCHEMBL12602929 | 0.65 | KDM4E (0.39) | KDM4EALDH1A1LMNAGAAHPGD | |
| SCHEMBL11808516 | 0.62 | BCHE (0.67) | KDM4EALDH1A1HPGD | |
| SCHEMBL3527227 | 0.62 | ALOX5 (0.46) | — | |
| SCHEMBL27985040 | 0.62 | GPR3 (0.64) | KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL2948928 | 0.61 | ALOX5 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041227-A1 | TETRACYCLIC HETEROCYCLE COMPOUNDS FOR TREATING HEPATITIS C VIRAL INFECTION | MERCK SHARP & DOHME CORP. (US) | 2012-04-05 | — | — | WO | disclosed |