Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAT2A | P31153 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | USP14 | P54578 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046000 | 0.83 | KDM4E (0.43) | NOTUMALDH1A1TSHRMAT2AKDM4E | |
| SCHEMBL9044837 | 0.83 | GLA (0.40) | NOTUMALDH1A1MAT2AKDM4EHPGD | |
| SCHEMBL12984605 | 0.75 | ALDH1A1 (0.63) | ALDH1A1TSHRKDM4EHPGDHSD17B10 | |
| SCHEMBL9564460 | 0.73 | LMNA (0.49) | ALDH1A1TSHRKDM4EHPGDHSD17B10 | |
| SCHEMBL9149430 | 0.73 | ALDH1A1 (0.79) | TDP1NOTUMALDH1A1TSHRKDM4E | |
| Bicarbonate SCHEMBL9044272 | 0.72 | RORC (0.47) | ALDH1A1TSHRKDM4EHPGDHSD17B10 | |
| SCHEMBL18919810 | 0.71 | ALDH1A1 (0.50) | TDP1NOTUMALDH1A1TSHRKDM4E | |
| SCHEMBL26596771 | 0.68 | ATM (0.58) | ALDH1A1MAT2AKDM4EMPIL3MBTL1 | |
| SCHEMBL14575529 | 0.67 | MAPK8 (0.51) | NOTUMMAT2AMAPK8MAPK9 | |
| SCHEMBL27758760 | 0.67 | ALDH1A1 (0.56) | TDP1NOTUMALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422485-B1 | Quinolone carboxylic acid derivatives, process for their preparation and their use | BAYER AG (DE) | 1996-04-03 | — | — | EP | disclosed |
| US-5300643-A | Viricides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-04-05 | — | — | US | disclosed |
| US-5217972-A | QUINOLONECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS ANTIVIRAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1993-06-08 | — | — | US | disclosed |
| EP-0422485-A2 | Quinolone carboxylic acid derivatives, process for their preparation and their use | BAYER AG (DE) | 1991-04-17 | — | — | EP | disclosed |