Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HTR1B | P28222 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564467 | 0.78 | KDM4E (0.41) | LMNAMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL9044266 | 0.73 | TDP1 (0.44) | LMNAKMT2AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL6807011 | 0.70 | LMNA (0.55) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9564472 | 0.67 | KDM4E (0.42) | LMNAMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL9564469 | 0.67 | LGMN (0.41) | LMNAMEN1KMT2AALDH1A1TP53 | |
| Difloxacin SCHEMBL148765 | 0.66 | LMNA (1.00) | LMNAMEN1KMT2AALDH1A1NPC1 | |
| Difloxacin SCHEMBL29695838 | 0.66 | LMNA (1.00) | LMNAMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL9564482 | 0.65 | KDM4E (0.38) | LMNAALDH1A1L3MBTL1NPC1RAB9A | |
| Difloxacin SCHEMBL203110 | 0.65 | LMNA (0.98) | LMNAMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL18861760 | 0.65 | ALDH1A1 (0.75) | LMNAMEN1KMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531958-A1 | 6-Aminoquinolones, their synthesis and their use as antibacterial agents | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1993-03-17 | — | — | EP | disclosed |