Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047016 | 0.84 | HSD17B10 (0.56) | ALDH1A1KDM4EMAPTLMNANPSR1 | |
| SCHEMBL9047335 | 0.79 | KMT2A (0.54) | LMNAKMT2AALPLALPIALPG | |
| SCHEMBL8189741 | 0.78 | MAPT (0.60) | ALDH1A1KDM4EMAPTLMNAKMT2A | |
| SCHEMBL9049481 | 0.78 | LMNA (0.55) | ALDH1A1KDM4EMAPTLMNAHTT | |
| SCHEMBL9116444 | 0.76 | PGR (0.56) | ALDH1A1KDM4EMAPTLMNAHTT | |
| SCHEMBL9049128 | 0.76 | SIRT2 (0.47) | KDM4EMAPTLMNAKMT2AMAPK1 | |
| SCHEMBL9053358 | 0.75 | PSEN1 (0.43) | ALDH1A1KDM4EPSEN1PSEN2APH1B | |
| SCHEMBL29622845 | 0.75 | KEAP1 (0.53) | ALDH1A1KDM4EMAPTLMNAHTT | |
| SCHEMBL113562 | 0.75 | KEAP1 (0.53) | ALDH1A1KDM4EMAPTLMNAHTT | |
| SCHEMBL8540234 | 0.72 | ALDH1A1 (0.61) | ALDH1A1KDM4EMAPTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0734378-A1 | AMINOSULPHONYL-PHENYL-1H-PYRROLE DERIVATIVES, METHOD OF THEIR PREPARATION AND THEIR USE | SMITHKLINE BEECHAM PLC (GB) | 1996-10-02 | — | — | EP | disclosed |