Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9045816 | 0.83 | KDM1A (0.43) | SMN1; SMN2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL9046300 | 0.83 | L3MBTL1 (0.39) | SMN1; SMN2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL9047524 | 0.82 | PTGS2 (0.42) | SMN1; SMN2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL9047068 | 0.81 | HTR1A (0.36) | SMN1; SMN2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL9046868 | 0.81 | LPAR1 (0.42) | SMN1; SMN2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL14341464 | 0.80 | ALOX5 (0.49) | SMN1; SMN2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL9045828 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL9045319 | 0.79 | GPR52 (0.46) | SMN1; SMN2CA12CA1CA2CA7 | |
| SCHEMBL4961769 | 0.78 | ALOX5 (0.42) | SMN1; SMN2CA12CA1CA2CA4 | |
| SCHEMBL9046887 | 0.75 | TAAR1 (0.39) | SMN1; SMN2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690854-A1 | 1-PHENYL-IMIDAZOL-2-ONE BIPHENYLMETHYL COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1996-01-10 | — | — | EP | disclosed |