Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 11/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9052806 | 0.83 | VNN1 (0.35) | DPP4DPP8DPP7HPSE | |
| SCHEMBL9046788 | 0.77 | DPP4 (0.39) | DPP4DPP8DPP7HDAC2FAP | |
| SCHEMBL9043752 | 0.71 | CHEK1 (0.30) | — | |
| SCHEMBL929673 | 0.70 | TACR3 (0.37) | — | |
| SCHEMBL25519257 | 0.66 | HSD11B1 (0.41) | HPGD | |
| SCHEMBL9210188 | 0.65 | RAB9A (0.43) | DPP4DPP8DPP7HDAC2HPGD | |
| SCHEMBL24936110 | 0.62 | — | — | |
| SCHEMBL22776034 | 0.62 | KDM4E (0.46) | — | |
| SCHEMBL11983395 | 0.61 | BRD4 (0.32) | L3MBTL1HPSE | |
| SCHEMBL9208317 | 0.60 | GID4 (0.41) | HDAC2L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743944-A1 | AZACYCLIC DERIVATIVES | SmithKline Beecham Farmaceutici S.p.A. (IT) | 1996-11-27 | — | — | EP | disclosed |
| WO-1995021843-A1 | AZACYCLIC DERIVATIVES | SMITHKLINE BEECHAM FARMACEUTICI S.P.A. (IT) | 1995-08-17 | — | — | WO | disclosed |