SCHEMBL9057637

SCHEMBL9057637

O=S(=O)(Oc1cccc(O)c1O)S(=O)(=O)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.41
ALDH1A1 P00352 3/20 0.41
ALOX15 P16050 3/20 0.41
HSD17B10 Q99714 3/20 0.41
LMNA P02545 2/20 0.41
HPGD P15428 2/20 0.41
KDM4E B2RXH2 2/20 0.41
MAPK1 P28482 2/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
ALOX12 P18054 1/20 0.41
HSD11B1 P28845 1/20 0.39
HSD17B3 P37058 1/20 0.39
MEN1 O00255 4/20 0.38
GAA P10253 4/20 0.38
KMT2A Q03164 4/20 0.38
ESR1 P03372 3/20 0.38
ESR2 Q92731 3/20 0.38
CA1 P00915 3/20 0.37
CA2 P00918 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5366223 0.82 HSD11B1 (0.55) MAPTALDH1A1ALOX15HSD17B10LMNA
SCHEMBL1879537 0.74 LMNA (0.50) MAPTALDH1A1ALOX15HSD17B10LMNA
SCHEMBL3480009 0.72 ALDH1A1 (0.54) MAPTALDH1A1ALOX15HSD17B10LMNA
Naphthalene SCHEMBL27698306 0.71 FABP1 (0.49) MAPTALDH1A1ALOX15HSD17B10LMNA
SCHEMBL679861 0.71 CA1 (0.52) MAPTALDH1A1HSD17B10LMNAMEN1
SCHEMBL8055874 0.71 KMT2A (0.56) MAPTALDH1A1ALOX15HSD17B10LMNA
SCHEMBL8379811 0.71 HSD11B1 (0.68) MAPTALDH1A1LMNAKDM4EMAPK1
SCHEMBL17004453 0.70 CA1 (0.50) MAPTALDH1A1HSD17B10LMNAMEN1
SCHEMBL29121430 0.70 CA1 (0.50) MAPTALDH1A1HSD17B10LMNAMEN1
Pyrogallol SCHEMBL2879498 0.70 TSHR (0.70) ALDH1A1ALOX15HSD17B10LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8158263-A None JP disclosed
JP-H08158263-A MODIFIED REGENERATED CELLULOSE FIBER FUJI SPINNING CO LTD 1996-06-18 JP disclosed