Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | TSPO | P30536 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24166883 | 0.83 | HSD11B1 (0.58) | HSD11B1MAOAMAOBALDH1A1RIPK1 | |
| SCHEMBL9191680 | 0.79 | RIPK1 (0.52) | ALOX5PTGS1PTGS2MAOAMAOB | |
| SCHEMBL1436622 | 0.77 | ALOX5 (0.70) | ALOX5PTGS1PTGS2ALDH1A1TSPO | |
| SCHEMBL3650924 | 0.76 | HSD11B1 (0.58) | HSD11B1MAOAMAOBALDH1A1RIPK1 | |
| SCHEMBL395409 | 0.76 | MEN1 (0.51) | HSD11B1MAOAMAOBALDH1A1OPRK1 | |
| SCHEMBL9192563 | 0.74 | PTGES (0.56) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9062790 | 0.74 | CYP1A2 (0.57) | MAOAMAOBALDH1A1 | |
| SCHEMBL9707266 | 0.74 | ALOX5 (0.61) | ALOX5PTGS1PTGS2ALDH1A1 | |
| SCHEMBL5711616 | 0.74 | MAOA (0.48) | HSD11B1MAOAMAOBALDH1A1CYP19A1 | |
| SCHEMBL30811414 | 0.74 | MAOA (0.48) | HSD11B1MAOAMAOBALDH1A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563136-A | ADMINISTERING FOR GASTROINTESTINAL OR NERVOUS SYSTEM DISORDERS CONNECTED WITH CHOLECYSTOKININ AND GASTRIN | RHONE-POULENC RORER S.A. (FR) | 1996-10-08 | — | — | US | disclosed |