Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | EYA2 | O00167 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2172604 | 0.83 | KDM4E (0.33) | KDM4EGAAHTT | |
| SCHEMBL9067904 | 0.74 | KMT2A (0.48) | KDM4EGAAHTTLMNA | |
| SCHEMBL11133634 | 0.71 | GAA (0.34) | GAAHTTTSHRLMNA | |
| SCHEMBL10456662 | 0.71 | NFKB1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL9812399 | 0.68 | OPRM1 (0.31) | TDP1EYA2APPACE | |
| SCHEMBL18439047 | 0.67 | ALDH1A1 (0.42) | TDP1LMNACHRM2SLC6A2SLC6A3 | |
| Bromoacetic Acid SCHEMBL1064789 | 0.66 | TSHR (0.48) | TSHRLMNA | |
| SCHEMBL31419341 | 0.66 | BLM (0.33) | BLMPMP22 | |
| SCHEMBL1769618 | 0.66 | HTT (0.37) | KDM4EGAAHTTLMNA | |
| Edetic Acid SCHEMBL3846372 | 0.64 | TDP1 (0.56) | KDM4ETDP1EYA2APPACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1333023-B1 | Immunogens, antibodies and conjugates to ketamine and its metabolites | RANDOX LAB LTD (GB) | 2010-12-22 | — | — | EP | disclosed |
| US-20090280499-A1 | METHOD AND KIT FOR DETECTING, OR DETERMINING 3,4- METHYLENEDIOXYMETHAMPHETAMINE | RANDOX LABORATORIES LIMITED (GB) | 2009-11-12 | — | — | US | disclosed |
| EP-1321772-B1 | Method and kit for detecting, or determining, 3,4-methylenedioxymethamphetamine | RANDOX LAB LTD (GB) | 2008-09-17 | — | — | EP | disclosed |
| US-7371829-B2 | Haptens, immunogens, antibodies and conjugates to ketamine and its metabolites | RANDOX LABORATORIES LIMITED (GB) | 2008-05-13 | — | — | US | disclosed |
| US-7217802-B2 | Method and kit for detecting, or determining, 3,4-methylenedioxymethamphetamine | RANDOX LABORATORIES LIMITED (IE) | 2007-05-15 | — | — | US | disclosed |
| EP-1312923-B1 | Method and kit for detecting, or determining the quantity of, metabolites of fentanyl and metabolites of fentanyl analogs | RANDOX LAB LTD (GB) | 2007-03-28 | — | — | EP | disclosed |
| US-7109310-B2 | Method and kit for detecting, or determining the quantity of, metabolites of fentanyl and metabolites of fentanyl analogs | RANDOX LABORATORIES, LTD. (IE) | 2006-09-19 | — | — | US | disclosed |
| US-20040121400-A1 | Method and kit for detecting, or determining, 3,4-methylenedioxymethamphetamine | NORTHERN BANK LIMITED (IE) | 2004-06-24 | — | — | US | disclosed |
| US-20030224447-A1 | Haptens, immunogens, antibodies and conjugates to ketamine and its metabolites | RANDOX LABORATORIES LIMITED | 2003-12-04 | — | — | US | disclosed |
| US-20030170728-A1 | Method and kit for detecting, or determining the quantity of, metabolites of fentanyl and metabolites of fentanyl analogs | RANDOX LABORATORIES LIMITED | 2003-09-11 | — | — | US | disclosed |
| EP-1333023-A1 | Haptens, immunogens, antibodies and conjugates to ketamine and its metabolites | Randox Laboratories Ltd. (GB) | 2003-08-06 | — | — | EP | disclosed |
| EP-1321772-A1 | Method and kit for detecting, or determining, 3,4-methylenedioxymethamphetamine | Randox Laboratories Ltd. (GB) | 2003-06-25 | — | — | EP | disclosed |
| EP-1312923-A2 | Method and kit for detecting, or determining the quantity of, metabolites of fentanyl and metabolites of fentanyl analogs | Randox Laboratories Ltd. (GB) | 2003-05-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040121400-A1 | Method and kit for detecting, or determining, 3,4-methylenedioxymethamphetamine | KIT, PNMT, HNMT | KDM4E 173/4885GAA 1375/4885HTT 265/4885 |
| US-20090280499-A1 | METHOD AND KIT FOR DETECTING, OR DETERMINING 3,4- METHYLENEDIOXYMETHAMPHETAMINE | KIT, PNMT, HNMT | KDM4E 189/4885GAA 1270/4885HTT 296/4885 |
| US-20030170728-A1 | Method and kit for detecting, or determining the quantity of, metabolites of fentanyl and metabolites of fentanyl analogs | OPRK1, KIT, OPRM1 | KDM4E 731/4885GAA 2441/4885HTT 1341/4885 |
| US-20030224447-A1 | Haptens, immunogens, antibodies and conjugates to ketamine and its metabolites | HNMT, HLA-DRB1, HLA-A | KDM4E 532/4885GAA 2296/4885HTT 112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.