Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2666963 | 0.77 | POLB (0.50) | L3MBTL1ALDH1A1PKMMEN1KMT2A | |
| SCHEMBL2667069 | 0.75 | DRD2 (0.39) | ALDH1A1HTR2CTSHRPOLBGAA | |
| SCHEMBL9071989 | 0.74 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL9072000 | 0.71 | HTR7 (0.40) | ALDH1A1ADRA1DADRA1A | |
| SCHEMBL1528354 | 0.70 | HSD17B10 (0.44) | ALDH1A1IRAK4CHRNA3MAPK1HSD17B10 | |
| SCHEMBL9071987 | 0.70 | GSK3B (0.40) | ADRA1A | |
| SCHEMBL1528355 | 0.70 | HSD17B10 (0.44) | ALDH1A1IRAK4CHRNA3MAPK1HSD17B10 | |
| SCHEMBL2667068 | 0.70 | HTR2C (0.40) | L3MBTL1ALDH1A1HTR2CMEN1USP2 | |
| SCHEMBL2666926 | 0.66 | MAOA (0.44) | L3MBTL1ALDH1A1HTR2CPKMMEN1 | |
| SCHEMBL2666928 | 0.66 | HTR2C (0.41) | L3MBTL1ALDH1A1HTR2CPKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007061923-A2 | GLUCOKINASE ACTIVATORS | TAKEDA SAN DIEGO, INC. (US) | 2007-05-31 | — | — | WO | disclosed |