Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 4/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9072000 | 0.85 | HTR7 (0.40) | ADRA1AADRA1DKDM4EALDH1A1 | |
| SCHEMBL2666963 | 0.81 | POLB (0.50) | POLBLMNAALDH1A1MAPT | |
| SCHEMBL9071987 | 0.79 | GSK3B (0.40) | DRD2ADRA1A | |
| SCHEMBL2667068 | 0.78 | HTR2C (0.40) | HTR2CHTR2BADRA1AADRA1DGAA | |
| SCHEMBL9071989 | 0.78 | L3MBTL1 (0.43) | POLBLMNAALDH1A1MAPTHTT | |
| SCHEMBL9071982 | 0.75 | L3MBTL1 (0.38) | HTR2CPOLBADRA1AADRA1DLMNA | |
| SCHEMBL2666926 | 0.75 | MAOA (0.44) | HTR2CHTR2BPOLBADRA1AADRA1D | |
| SCHEMBL2666928 | 0.74 | HTR2C (0.41) | DRD2HTR2CHTR2BPOLBADRA1A | |
| SCHEMBL9072147 | 0.71 | DHFR (0.51) | POLBLMNATSHRGAAKDM4E | |
| SCHEMBL2666743 | 0.70 | PKM (0.41) | HTR2CHTR2BPOLBHTR2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007061923-A2 | GLUCOKINASE ACTIVATORS | TAKEDA SAN DIEGO, INC. (US) | 2007-05-31 | — | — | WO | disclosed |