Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | HTR1B | P28222 | 3/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | LSS | P48449 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667069 | 0.85 | DRD2 (0.39) | KDM4EALDH1A1ADRA1DADRA1A | |
| SCHEMBL2666963 | 0.77 | POLB (0.50) | ALDH1A1 | |
| SCHEMBL9071987 | 0.75 | GSK3B (0.40) | ADRA1A | |
| SCHEMBL2667068 | 0.75 | HTR2C (0.40) | KDM4EALDH1A1ADRA1DADRA1A | |
| SCHEMBL9071989 | 0.74 | L3MBTL1 (0.43) | ALDH1A1 | |
| SCHEMBL9071982 | 0.71 | L3MBTL1 (0.38) | ALDH1A1ADRA1DADRA1A | |
| SCHEMBL2666926 | 0.71 | MAOA (0.44) | ALDH1A1ADRA1DADRA1A | |
| SCHEMBL2666928 | 0.70 | HTR2C (0.41) | MAP1LC3BALDH1A1ADRA1DADRA1A | |
| SCHEMBL30492994 | 0.70 | HTR7 (0.64) | HTR7HTR1BHRH1ALDH1A1LSS | |
| SCHEMBL2666743 | 0.67 | PKM (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007061923-A2 | GLUCOKINASE ACTIVATORS | TAKEDA SAN DIEGO, INC. (US) | 2007-05-31 | — | — | WO | disclosed |