Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13719241 | 0.89 | EPHX2 (0.46) | HRH3TSHRPKMHTTCYP2C9 | |
| SCHEMBL27792952 | 0.87 | HRH3 (0.43) | HRH3TSHRPKMSMN1; SMN2HTT | |
| SCHEMBL28898278 | 0.79 | RXRA (0.46) | PKMSMN1; SMN2MAPTEGFRLMNA | |
| SCHEMBL9081693 | 0.78 | LMNA (0.47) | PKMSMN1; SMN2MAPTHTTEGFR | |
| SCHEMBL16731569 | 0.78 | KMT2A (0.49) | PKMSMN1; SMN2MAPTHTTLMNA | |
| SCHEMBL6862344 | 0.78 | L3MBTL1 (0.49) | TSHRPKMSMN1; SMN2MAPTLMNA | |
| SCHEMBL6393097 | 0.77 | ALDH1A1 (0.57) | PKMSMN1; SMN2MAPTLMNAKMT2A | |
| SCHEMBL23115223 | 0.77 | MEN1 (0.46) | TSHRSMN1; SMN2MAPTLMNAKMT2A | |
| SCHEMBL3410566 | 0.77 | PTGDR2 (0.48) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL6208833 | 0.76 | CYP4Z1 (0.43) | PKMSMN1; SMN2MAPTEGFRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070140973-A1 | CONTRAST AGENTS FOR MYOCARDIUM PERFUSION IMAGING | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2007-06-21 | — | — | US | disclosed |
| US-20070140973-A1 | CONTRAST AGENTS FOR MYOCARDIUM PERFUSION IMAGING | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2007-06-21 | — | — | US | disclosed |
| WO-1996034851-A1 | BENZENE, PYRIDINE, NAPHTALENE OR BENZOPHENONE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHETASE AND PROTEIN FARNESYLTRANSFERASE | ABBOTT LABORATORIES (US) | 1996-11-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070140973-A1 | CONTRAST AGENTS FOR MYOCARDIUM PERFUSION IMAGING | TNNI3, TNNT2, TNNC1 | HRH3 2569/4885TSHR 2938/4885PKM 1341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.