SCHEMBL9083549

SCHEMBL9083549

COc1cc(OC)nc(SC(C(=O)N(C)[C@@H](C)C(=O)OC(C)(C)C)C(C)C)n1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
ADORA3 P0DMS8 2/20 0.31
CYP1A2 P05177 1/20 0.31
ADORA1 P30542 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9230745 0.85 ALOX5 (0.36) ALDH1A1ADORA3ADORA1
SCHEMBL9083868 0.78 EDNRB (0.39)
SCHEMBL9401416 0.76 CYP1A2 (0.42) ALDH1A1ADORA3CYP1A2ADORA1
SCHEMBL13851482 0.74 ALOX5 (0.44) ALDH1A1CYP1A2
SCHEMBL9082975 0.74 ALOX5 (0.44) ALDH1A1CYP1A2
SCHEMBL16160330 0.74 CYP1A2 (0.44) ALDH1A1ADORA3CYP1A2ADORA1
SCHEMBL13851483 0.74 ALOX5 (0.44) ALDH1A1CYP1A2
SCHEMBL9388253 0.72 LMNA (0.38) ALDH1A1ADORA3CYP1A2ADORA1
SCHEMBL9388237 0.71 ADORA3 (0.41) ALDH1A1ADORA3ADORA1
SCHEMBL9388381 0.71 ALDH1A1 (0.34) ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0601155-A1 PYRIMIDINYL-AND TRIAZINYL COMPOUNDS WITH HERBICIDAL ACTIVITY Novartis AG (CH) 1994-06-15 EP claimed
WO-1993025540-A1 PYRIMIDINYL-AND TRIAZINYL COMPOUNDS WITH HERBICIDAL ACTIVITY CIBA-GEIGY AG (CH) 1993-12-23 WO claimed
US-5482920-A Triazinyl compounds with herbicidal activity CIBA-GEIGY CORPORATION (US) 1996-01-09 US disclosed
EP-0601155-A1 PYRIMIDINYL-AND TRIAZINYL COMPOUNDS WITH HERBICIDAL ACTIVITY Novartis AG (CH) 1994-06-15 EP disclosed
WO-1993025540-A1 PYRIMIDINYL-AND TRIAZINYL COMPOUNDS WITH HERBICIDAL ACTIVITY CIBA-GEIGY AG (CH) 1993-12-23 WO disclosed